Repellent and Anti-quorum Sensing Activity of Six Aromatic Plants Occurring in Colombia

Abstract

Essential oils (EOs) are widely used as biopesticides and to control bacterial infections. This study describes the ability of six EOs isolated from plants cultivated in Colombia to perform as repellents against Ulomoides dermestoides and as quorum sensing (QS) inhibitors. EOs from Aloysia triphylla, Cymbopogon nardus, Lippia origanoides, Hyptis suaveolens, Swinglea glutinosa and Eucalyptus globulus were repellents classified as Class IV, IV, IV, III, II, and II, respectively, whereas the commercial repellent IR3535 only reached Class II after 2 h exposure. All EOs presented small, but significant inhibitory properties against the QS system in Escherichia coli (pJBA132) at 25 µg/mL after 4 h exposure. These data suggest evaluated EOs from Colombia are sustainable, promising new sources of natural repellents and could be important as anti-quorum sensing molecules.

Essential Oils of Aromatic Plants with Antibacterial, Anti-Biofilm and Anti-Quorum Sensing Activities against Pathogenic Bacteria

“…Cervantes and coworkers did report a poor anti-QS activity of the essential oils from Lippia origanoides at the concentrations tested (2.5-25.0 µg/mL). However, note that thymol and carvacrol metabolites were present in low concentrations in such EO, and thereby it highlights the importance of these metabolites as the ones responsible for the anti-QS activity [43]. In addition, carvacrol oil in a range of 0.1 to 0.4 mM, has been reported for strongly inhibit violacein production, highlighting the importance of this metabolite in bacterial QS [24].…”

A Review: The extraction of active compound from Cymbopogon sp. and its potential for medicinal applications

“…Current practices involve the use of general methods of extraction that have been well developed due to the application of advanced technology. These extraction methods are known as Soxhlet extraction [43]- [45], microwave-assisted extraction [22], [44]- [50], ultrasound extraction [33], [34], [51], supercritical fluid extraction [11], [20], [27], [52], [53], hydrodistillation [22], [24], [44], [49], [54], [55] and steam distillation [14], [52], [56]- [62], [63], [64]. Each process is unique in terms of the process principal and process parameters, however the selection basis is generally depending on the yield of the process [52], [59], [65].…”

“…The extracts from Cymbopogon normally exist in several forms, liquid [36], [39] and oil [4], [10], [16], [22]- [28], [33], [34]. The oil-based extract is normally known as essential oil and this product has been widely used as insect repellent to kill the Aedes mosquitoes [5], [26], [31], [32], [37], [40], [51] alternative medicines [2], [35], [59], [66] aromatherapy and cosmetic [2], [10], [27], [33]- [35], [39], [67]- [69]. Due to its nice odour, Cymbopogon sp.…”

Antimicrobial activity of Eucalyptus camaldulensis Dehn. plant extracts and essential oils: A review

“…This communication system is relative to cell density and some compounds interfere with the QS communication system and attenuating the bacterial pathogenicity, in the phenomenon known as anti-QS compounds (Abraham et al, 2011). There are reports of anti-QS activity of various plants species EOs from genus Eucalyptus, such as Eucalyptus globulus L. (Luís et al, 2016;Cervantes-Ceballos et al, 2015), Eucalyptus radiata D. (Luís et al, 2016), Eucalyptus citriodora Hook., Eucalyptus smithii R. T. Baker and Eucalyptus staigeriana F. Muell. ex Bailey (Luís et al, 2016).…”