The energy deficiency in rural housing in the Andes of Peru is recurrent. In this context, local and low environmental impact materials present an opportunity. This research evaluated the properties of five panels composed of totora and gypsum for ceiling applications. Firstly, the physical and durability properties were obtained. Then, impact and fire resistance were evaluated. Finally, thermoacoustic properties were assessed. The results showed a moisture level of 10.25%, water absorption of 354.85% which is considered high, and a dry density of 292.84 kg/m3. Adequate durability to fungus with resin on both sides. The panels’ fire resistance is superior to 60 minutes, with a safe impact criterion for 10 N and a functionality criterion for 5 N. The average values for the panels were 0.061 W/m·K for thermal insulation and 0.54 for NRC. Therefore, it is possible to produce an insulating material for thermoacoustic improvement.