2024
DOI: 10.3390/ijms25168819
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Repetitive Sequence Stability in Embryonic Stem Cells

Guang Shi,
Qianwen Pang,
Zhancheng Lin
et al.

Abstract: Repetitive sequences play an indispensable role in gene expression, transcriptional regulation, and chromosome arrangements through trans and cis regulation. In this review, focusing on recent advances, we summarize the epigenetic regulatory mechanisms of repetitive sequences in embryonic stem cells. We aim to bridge the knowledge gap by discussing DNA damage repair pathway choices on repetitive sequences and summarizing the significance of chromatin organization on repetitive sequences in response to DNA dama… Show more

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