Repigmentation of hair associated with melanoma in situ of scalp

Tiger, Jeffrey B.; Habeshian, Kaiane; Barton, Dorothea T.; Brennick, Jeoffry B.

doi:10.1016/j.jaad.2014.05.019

Cited by 9 publications

(10 citation statements)

References 4 publications

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“…Furthermore, there are also many reports of non-drug related hair repigmentation such as the presence of adjacent melanoma [47][48][49][50][51] , actinic granuloma [52] , epilation [53] , hair transplant [54] , zoster [55] , spontaneous [56][57][58][59] and X-ray irradiation or electron beam exposure [60] .…”

Section: Discussionmentioning

confidence: 99%

Lamivudine associated hair repigmentation and a comprehensive review on reversal canities

Ghassemi¹,

Behrangi²,

Roohaninasab³

et al. 2021

PJMHS

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Background and Objective: Hair whitening is among important cosmetic problems in both genders but more annoying between women which necessitates more research about hair repigmenting methods or probable therapeutic drugs. The objective of this research was to review the mechanisms of hair pigmentation as well as the drug-related hair repigmentation. Methods: In this review article, we searched PubMed, Medline and Google scholar databases and reviewed all related articles in this area (hair repigmentation) since the reversal of canities has been an important cosmetic concern many years ago. Results: No reports of changes of hair color have been identified with lamivudine in the present research. Herein can be reported as the first case of hair repigmentation following the use of lamivudine. Conclusion: We reported a case of hair pigmentation with lamivudine for the first time that could be a desirable drug-induced side effect, also review all related articles about hair repigmention or reversal of canities. By research on probable mechanisms of drug-induced hair repigmentation, we may achieve a therapeutic strategy of hair graying as an important and highly prevalent cosmetic concern. Keywords: Lamivudine; hair repigmentation; reversal canities; drug-induced, review

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Section: Discussionmentioning

confidence: 99%

Lamivudine associated hair repigmentation and a comprehensive review on reversal canities

Ghassemi¹,

Behrangi²,

Roohaninasab³

et al. 2021

PJMHS

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“…In this setting, poliosis is likely occurring as a consequence of an immunological response to an underlying malignant melanoma. To our knowledge, hair repigmentation has been described in only 4 prior case reports [5][6][7][8]. Inzinger et al reported a case of a 91-year-old woman with a 10-year history of hair re-pigmentation in the setting of a 3.5mm thick, stage IIIB melanoma with evidence of invasion within hair follicles on histology [6].…”

Section: Discussionmentioning

confidence: 99%

“…Inzinger et al reported a case of a 91-year-old woman with a 10-year history of hair re-pigmentation in the setting of a 3.5mm thick, stage IIIB melanoma with evidence of invasion within hair follicles on histology [6]. Three other published cases reports describe hair re-pigmentation in the setting of scalp melanomas without melanocytic invasion into hair follicles: a 7mm thick, amelanotic desmoplasic scalp melanoma and 2 cases of scalp lentigo maligna [5,7,8]. In our case and the 4 previously published cases, a diagnosis of melanoma could have been made earlier if hair re-pigmentation was recognized as a concerning feature for melanoma by either the patient or clinician.…”

Section: Discussionmentioning

confidence: 99%

A case of hair re-pigmentation from a scalp melanoma

Oza

Schulman²,

Mully³

et al. 2015

Dermatology Online Journal

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was a type II Fitzpatrick skin phototype. Golden blond/brown hair was noted on her central vertex scalp in the setting of decreased hair density with grey/white hair throughout the rest of her scalp.2) Within the area of the hair color change, a 1.9 by 0.9cm grey-black nodule with an area of focal crust was noted. Two non-contiguous grey-black papules were noted 1cm away from the primary nodule representing satellite lesions Volume 21 Number 7 July 2015 Case presentation A case of hair re-pigmentation from a scalp melanoma

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“…Repigmentation also has been reported in malignant melanoma, as documented in our patient, as well as desmoplastic and amelanotic melanoma. 5,6 In every case, the color of the repigmentation was darker than the rest of the patient's hair; however, the repigmentation color can be different from the patient's original hair color from their youth. 4,5,11 The exact mechanism responsible for hair repigmentation in the setting of melanoma is unclear.…”

mentioning

confidence: 97%

“…Based on a PubMed search of articles indexed for MEDLINE using the terms hair repigmentation and melanoma, there have been 11 other reported cases of hair repigmentation associated with melanoma (Table ). [3][4][5][6][7][8][9][10][11][12][13] It initially was suspected that this rare phenomenon primarily existed in the female population, as the first 5 cases were reported solely in females, [3][4][5][6][7] possibly due to the prevalence of androgenetic alopecia in males. 11 However, 6 cases of repigmentation associated with melanoma were later reported in males [8][9][10][11][12][13] ; our patient represents an additional reported case in a male.…”

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confidence: 99%