Traumatic injuries with loss of anterior teeth occur more frequently in children. Treatment of the dental trauma is complex and requires a comprehensive and accurate diagnostic and treatment plan. It is also important to consider the biological, functional, esthetic, and economic aspects. The purpose of this article is to show a case report with a successful root formation and periodontal healing after autotransplantation of maxillary second right premolar in place of maxillary right central incisor site. Tooth autotransplantation may be considered as a viable treatment option instead of a conventional prosthetic and implant rehabilitation.