Reply to S. E. Taylor from E. Y. Sheu and D. A. Storm

Sheu, Eric Y.; Storm, David A.

doi:10.1016/0016-2361(94)90316-6

Cited by 61 publications

(105 citation statements)

References 6 publications

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“…The expression vectors also maintained the ability to secrete all three envelope antigens, implying that no extreme misfolding had occurred as the result of the mutagenesis or lack of glycosylation (data not shown). This is consistent with the results obtained with tunicamycin (7)(8)(9), and further shows that the secretion of subviral particles is independent of N-linked glycosylation.…”

Section: Resultssupporting

confidence: 92%

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Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion

Mehta

Block

et al. 1997

Proc. Natl. Acad. Sci. U.S.A.

124

102

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Section: Resultssupporting

confidence: 92%

“…The role of N-linked glycosylation in HBV has yet to be determined. Several reports have provided evidence that the N-linked glycans are not necessary for the secretion of the subviral particle (7,8). In contrast, the secretion of virus requires both N-linked glycosylation (9) and N-linked glycan processing (10).…”

mentioning

confidence: 99%

Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion

Mehta

Block

et al. 1997

Proc. Natl. Acad. Sci. U.S.A.

124

102

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“…Strain Orc-4 T had a fatty acid profile similar to those of the other eight species (Table 1). The dominant fatty acid was C 18 : 1 v7c for the novel strain and the eight closest relatives, which is consistent with those of previous publications (Rothe et al, 1987;Liu et al, 2010;Zheng et al, 2011;Zhang et al, 2012;Chen et al, 2013;Sheu et al, 2013). Furthermore, strain Orc-4 T differed from the eight closest relatives in the proportions of some minor fatty acids.…”

Section: Rhodobacter Ovatus Ja234 T (Am690348)supporting

confidence: 91%

“…S1, available in IJSEM Online). Strain Orc-4 T exhibited a very similar polar lipid profile to its eight closest relatives Sheu et al, 2013): they all contained PE, PG, PC and AL. However, the results suggested that there are some differences in the polar lipid profiles of these organisms.…”

Section: Rhodobacter Ovatus Ja234 T (Am690348)mentioning

confidence: 98%

“…For unsaturated fatty acids, the position of the double bond is located by counting from the methyl (v) end of the carbon chain. On: Thu, 10 May 2018 10:00:18 Rothe et al, 1987;Tanaka et al, 2004;Anil Kumar et al, 2007;Liu et al, 2010;Zheng et al, 2011;Zhang et al, 2012;Chen et al, 2013;Sheu et al, 2013). +, Positive reaction; 2, negative reaction.…”

Section: Rhodobacter Ovatus Ja234 T (Am690348)mentioning

confidence: 99%

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Gemmobacter lanyuensis sp. nov., isolated from a freshwater spring

Sheu

Shiau

Wei

et al. 2013

International Journal of Systematic and Evolutionary Microbiology

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A bacterial strain designated Orc-4 T was isolated from a freshwater spring in Taiwan and characterized using the polyphasic taxonomic approach. Cells of strain Orc-4 T were facultatively anaerobic, Gram-reaction-negative, poly-b-hydroxybutyrate-accumulating, non-motile rods surrounded by a thick capsule and forming cream-white colonies. Growth occurred at 15-40 6C (optimum, 25-30 6C), at pH 6.0-9.0 (optimum, pH 7.0) and with 0-1 % NaCl (optimum, 0-0.5 %). Phylogenetic analyses based on 16S rRNA gene sequences showed that strain Orc-4 T belonged to the genus Gemmobacter within the family Rhodobacteraceae of the class Alphaproteobacteria and its most closely related neighbour was Gemmobacter fontiphilus JS43 T with sequence similarity of 97.8 %. Strain Orc-4 T contained C 18 : 1 v7c as the predominant fatty acid. The major respiratory quinone was Q-10. The DNA G+C content of the genomic DNA was 63.5 mol%. The polar lipid profile consisted of a mixture of phosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine, one uncharacterized aminolipid and several uncharacterized phospholipids. The DNA-DNA relatedness of strain Orc-4 T with respect to recognized species of the genus Gemmobacter was less than 48 %. On the basis of the genotypic, chemotaxonomic and phenotypic data, strain Orc-4 T represents a novel species of the genus Gemmobacter, for which the name Gemmobacter lanyuensis sp. nov. is proposed. The type strain is Orc-4 T

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Quantum Logic Gates Based on DNAtronics, RNAtronics, and Proteintronics

Sheu

Hsu

Yang

2021

Advanced Intelligent Systems

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A quantum computer (QC) [1][2][3] implements quantum bits (qubits) and qudits [4] (e.g., qutrits [5] and ququarts [6] ) to conduct computations instead of a traditional digital computer built from a transistor in which a binary bit is represented by either 1 or 0. Based on the Church-Turing-Deutch principle, a computing machine conducts simulations of every physical process and behaves as a universal QC. [7][8][9] Unlike a classical bit, the basic unit of a qubit is the superposition c 0 j0i þ c 1 j1i of two qubit states, j0i and j1i, where c 0 and c 1 denote complex numbers. [10] However, the operation of a QC with a relatively large number of qubits for conducting universal computations has attracted considerable attention. [11] Using quantum algorithms such as Shor's algorithm, [12] a quantum many-body simulation [10] and Simon's algorithm, [13] a large-scale QC could tackle problems faster than a classical computer. Until now, present quantum algorithms have been implemented by superconducting flux qubits (D-wave systems), [14] nuclear magnetic resonance (NMR) techniques, [15,16] photonic QCs, [17] and ion-trap systems. [18,19] For NMR techniques, Shor's factorizing algorithm, [20] which uses seven qubits, has been applied. The qubits are encoded in mixed states, and the output is a result of an ensemble measurement. Hence, NMR QCs are not scalable. [21] For a trapped-ion QC, the qubits are stored in the electronic states of ions and are controllable in long-lived internal states, and their quantum states can be detected with a very high efficiency close to 100%. [19,22,23] These characteristics permit the manipulation of pure states to build a scalable and universal QC. [24] Nevertheless, no quantum logic gate has been executed with a subnano-scaled molecular transistor to date.Classical computers operate with a microprocessor that consists of semiconductor logic gates with electronic input and output signals of a binary digital nature. The output can be only one of the two states, on or off, corresponding to logic 1 or 0, respectively. Consequently, the signal pattern can be described by a truth table based on Boolean algebra. [25] This critical feature in constructing computers could be conducted by a single-molecule transistor as a future classical computer. [26,27] However, accomplishing concerted arrays of molecular transistors remains an intrinsic challenge. [28,29] Recently, several experiments have shown the feasibility of conducting computations at the molecular level. For example, DNA is a reliable biomolecule and can be used to build molecular computation systems; however, it was used as a classical liquid computer to solve the Hamiltonian path problem. [30] DNA-based logic gates [25,31] have been designed by deoxyribozyme ligases. [32,33] It is possible to integrate the logic gates into simple circuits using a series of deoxyribozyme ligases communicating via a deoxyribozyme phosphodiesterase. [28] Meanwhile, NOT and two-input AND gates were integrated into an INHIBIT logic gate, and signal trans...

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Reply to S. E. Taylor from E. Y. Sheu and D. A. Storm

Cited by 61 publications

References 6 publications

Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion

Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion

Gemmobacter lanyuensis sp. nov., isolated from a freshwater spring

Quantum Logic Gates Based on DNAtronics, RNAtronics, and Proteintronics

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