Reply to Sentinel Lymph Node in Vulvar Cancer

A Prospective Study of Sentinel Lymph Node Detection in Vulval Carcinoma: Is It Time for a Change in Clinical Practice?

“…We had 5 such cases where Tc99m and blue dye were injected around the scar of a previously completely removed vulval tumor. In our experience, the detection rate in these cases is 100% without any false-negative results similar to Hauspy et al 16 This study demonstrates that SLN detection is still reliable when injecting around a previous surgical excision site. However, Vidal-Sicart et al 13 reported 1 case where they could not detect the SLN after injection around the scar after tumor excision.…”

“…8,15,21 Published data indicate that the detection rate is satisfactory, the majority reporting close to 100% using the combined method. 15,16 In vulval carcinoma, the reported false-negative results are 0 to 7.7%. 10,16,17 However, most studies reported on a small number of patients, with some studies using the single method and with others using the combined technique.…”

“…15,16 In vulval carcinoma, the reported false-negative results are 0 to 7.7%. 10,16,17 However, most studies reported on a small number of patients, with some studies using the single method and with others using the combined technique. In our study, the combined method did not result in any false-negative cases.…”

Effects of Previous Surgery on the Detection of Sentinel Nodes in Women With Vulvar Cancer

“…6,9,14,17,18 One of the reasons is that part of the bilateral/midline tumors in reality has only unilateral drainage. However, detection of bilateral SNs may also be hampered by firm nodal metastases, which should be considered a potential pitfall.…”