Report 16: Role of testing in COVID-19 control

Grassly, Nicholas C.; Salort, M Pons; Parker, Emma; White, P. A. F.; Ainslie, Kylie E. C.; Baguelin, Marc; Bhatt, S; Boonyasiri, Adhiratha; Boyd, Olivia; Brazeau, Nicholas F.; Cattarino, Lorenzo; Ciavarella, Constanze; Cooper, Laura V; Coupland, Helen; Perez, Z Cucunuba; Cuomo-Dannenburg, Gina; Dighe, Amy; Djaafara, A; Donnelly, C; Dorigatti, Ilaria; Elsland, S Van; Nascimento, Fabrícia F.; Fitzjohn, R; Fu, Hui‐Jun; Gaythorpe, Katy A. M.; Geidelberg, Lily; Green, W; Hallett, Timothy B.; Hamlet, Arran; Hayes, S; Hinsley, Wes; Imai, Natsuko; Jorgensen, David A.; Knock, Edward; Laydon, Daniel J.; Lees, Jonathan G.; Mangal, Tara; Mellan, Thomas A.; Mishra, Sai Bhakti; Gilani, G Nedjati; Nouvellet, Pierre; Okell, Lucy; Ower, Alison; Parag, Kris V; Pickles, Michael; Ragonnet‐Cronin, Manon; Stopard, Isaac J.; Thompson, Hayley; Unwin, H. Juliette T.; Verity, Robert; Vollmer, Michaela; Volz, E; Walker, Patrick; Walters, Caroline E.; Wang, H; Wang, Y; Watson, O; Whittaker, C; Whittles, Lilith K; Winskill, Peter; Xi, Xin; Ferguson, Neil

doi:10.25561/78439

Cited by 7 publications

(1 citation statement)

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“…O primeiro caso registrado em território inglês se deu em 31 de janeiro de 2020. Já em março do mesmo ano a Europa era considerada, segundo a OMS, o epicentro da pandemia no mundo 9 . Àquela altura, dificuldades semelhantes às vividas pelo Brasil atualmente eram experimentadas pelo Reino Unido, e o primeiro-ministro Boris Johnson sofria pressão pela sua aparente incapacidade de lidar com a pandemia 10 11 .…”

Section: A Pandemia Na Inglaterraunclassified

A Gestão De Riscos À Luz Da Pandemia Do Novo Coronavírus (Covid-19): Uma Análise Das Ações Estratégicas De Enfrentamento Adotadas Por Dois Países

Souza¹,

Silva²

2021

Administração Pública: Desafios E Perspectivas Da Gestão Pública Pós Pandemia

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Section: A Pandemia Na Inglaterraunclassified

A Gestão De Riscos À Luz Da Pandemia Do Novo Coronavírus (Covid-19): Uma Análise Das Ações Estratégicas De Enfrentamento Adotadas Por Dois Países

Souza¹,

Silva²

2021

Administração Pública: Desafios E Perspectivas Da Gestão Pública Pós Pandemia

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Protecting healthcare workers from SARS-CoV-2 and other infections

2020

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Coronavirus disease 2019 (COVID-19) has had a tremendous impact in China and abroad since its onset in December 2019 and poses a major threat to human health. Healthcare workers (HCWs) are at the forefront of the response to outbreaks. This study reviewed literature data and found that HCWs were at high risk of infection during the COVID-19 pandemic, especially at the early stage of the epidemic, and many factors greatly affected their occupational safety. Although SARS-CoV-2 transmission was controlled in China, the Chinese experience can help protect HCWs from COVID-19 and other respiratory diseases.

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A Modelling Study for Designing a Multi-layered Surveillance Approach to Detect the Potential Resurgence of SARS-CoV-2

Liu

Gong

Clifford

et al. 2020

Preprint

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Background: Countries achieving control of COVID-19 after an initial outbreak will continue to face the risk of SARS-CoV-2 resurgence. This study explores surveillance strategies for COVID-19 containment based on polymerase chain reaction tests. Methods: Using a dynamic SEIR-type model to simulate the initial dynamics of a COVID-19 introduction, we investigate COVID-19 surveillance strategies among healthcare workers, hospital patients, and community members. We estimate surveillance sensitivity as the probability of COVID-19 detection using a hypergeometric sampling process. We identify test allocation strategies that maximise the probability of COVID-19 detection across different testing capacities. We use Beijing, China as a case study. Findings: Surveillance subgroups are more sensitive in detecting COVID-19 transmission when they are defined by more COVID-19 specific symptoms. In this study, fever clinics have the highest surveillance sensitivity, followed by respiratory departments. With a daily testing rate of 0.07/1000 residents, via exclusively testing at fever clinic and respiratory departments, there would have been 598 [95% eCI: 35, 2154] and 1373 [95% eCI: 47, 5230] cases in the population by the time of first case detection, respectively. Outbreak detection can occur earlier by including non-syndromic subgroups, such as younger adults in the community, as more testing capacity becomes available. Interpretation: A multi-layer approach that considers both the surveillance sensitivity and administrative constraints can help identify the optimal allocation of testing resources and thus inform COVID-19 surveillance strategies. Funding: Bill & Melinda Gates Foundation, National Institute of Health Research (UK), National Institute of Health (US), the Royal Society, and Wellcome Trust.

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Report 16: Role of testing in COVID-19 control

Cited by 7 publications

References 0 publications

A Gestão De Riscos À Luz Da Pandemia Do Novo Coronavírus (Covid-19): Uma Análise Das Ações Estratégicas De Enfrentamento Adotadas Por Dois Países

A Gestão De Riscos À Luz Da Pandemia Do Novo Coronavírus (Covid-19): Uma Análise Das Ações Estratégicas De Enfrentamento Adotadas Por Dois Países

Protecting healthcare workers from SARS-CoV-2 and other infections

A Modelling Study for Designing a Multi-layered Surveillance Approach to Detect the Potential Resurgence of SARS-CoV-2

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