Report of a human fatality due to amphetamine

Hoof, F. Van; Heyndrickx, A; Timperman, J

doi:10.1007/bf00330112

Cited by 12 publications

(11 citation statements)

References 4 publications

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“…Decedents suffer nervousness, hyperthermia, convulsion, cardiac and respiratory failure prior to death [13]. Postmortem toxicology of amphetamine-related fatalities has rarely been reported, and most existing reports are dated in the 1970s [14][15][16][17], primarily reporting single-case investigations [15,[18][19][20] or epidemiological studies involving large numbers of amphetamine-related fatalities [6,21]. It is common to detect amphetamines in postmortem specimens, but interpreting their contribution to fatalities is difficult.…”

Section: Introductionmentioning

confidence: 99%

Post-Mortem Quantitation of Amphetamine in Cadaveric Fluids in Saudi Arabia

et al. 2022

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Amphetamine abuse is a known problem in Saudi Arabia; it is estimated that 40% of drug abusers misuse amphetamines. Here, our aim was to perform an up-to-date epidemiological study of amphetamine-related postmortem cases in Jeddah, Saudi Arabia, in which 235 postmortem cases were included. The largest number of cases was recorded for the groups aged between 31 and 40 years (86 cases) and the lowest number of cases was recorded for the group aged between 61 and 70 years old (5 cases). Amphetamine was co-ingested with other drug(s) in 55% of the total cases (blood with sodium fluoride (BN), median, 0.3 mg/L). Approximately 23% of all deaths were due to other co-ingested drugs (BN, median, 0.2 mg/L). Amphetamines alone were detected in 107 cases, (BN, median, 0.5 mg/L). Amphetamine was the sole cause of death in 16% of the studied cases (BN, median, 1.0 mg/L). The combination of amphetamine and a pre-existing disease were observed in 9.4% of all deaths (BN, median, 0.7 mg/L). The causes of death were determined to be accidental in the majority (47%) of cases, homicides in 26% of cases, suicides in 11% of cases, and unknown in 7% of cases. This is the first discussion of the amphetamine concentration in bile in amphetamine-related deaths, the relationship between amphetamine concentration in different bodily fluids, and the amphetamine concentration in putrefied corpses. This study concluded that amphetamine abuse in Jeddah, Saudi Arabia, increased over 400% between 2012 and 2018, and 41% of these cases involved violence. This result also suggests that preventive programs targeting youth and adolescent students are required to keep schools and universities free from drugs, especially amphetamines.

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Section: Introductionmentioning

confidence: 99%

Post-Mortem Quantitation of Amphetamine in Cadaveric Fluids in Saudi Arabia

et al. 2022

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“…The recent use of lasers instead of conventional arc lamps is a convenient and powerful way to significantly improve the light source and hence improve the sensitivity. In certain cases, photodegradation or photochemical reactions can be worrisome (13), but the higher photon densities and spatial coherence of lasers have permitted the extension of the limits of fluorescence detection in solution by orders of magnitude for certain laser dyes (14) and riboflavin (15). Laser excitation has also lowered the detection limits for flame atomic fluorescence ( 16…”

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confidence: 99%

Determination of gentamicin complex components in fermentation broth by in-situ fluorimetric measurements of 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole derivatives

Kabasakalian¹,

Kalliney²,

Magatti³

1977

Anal. Chem.

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“…Sci., 60, 461 (1971), NBD-CI was first used by Ghosh and Whitehouse as a labeling agent for amino acids (6). NBD-CI was applied in former studies for identification of phenylethylamines (7)(8)(9) and for quantitative determination of carbamate insecticides (10,11) and dithiocarbamate fungicides (12).…”

mentioning

confidence: 99%