1991
DOI: 10.1159/000133161
|View full text |Cite
|
Sign up to set email alerts
|

Report of the committee on the genetic constitution of chromosome 1

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

4
28
1

Year Published

1991
1991
2001
2001

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 32 publications
(33 citation statements)
references
References 19 publications
4
28
1
Order By: Relevance
“…DNA samples were subjected to microsatellite marker analysis to know parent-child transmissions of alleles on chromosome 1 as well as on other autosomes. Highly polymorphic microsatellite markers at 102 loci were selected, including 47 dinucleotide and three tetranucleotide repeat markers spanning chromosome 1, and 52 dinucleotide repeats on chromosomes 2-22, according to the maps reported by Bruns et al [1995] and by Dib et al [1996] and those obtained through internet database (Cooperative Human Linkage Center Integrated Maps, CHLC Integrated Maps, http://www.chlc.org; Human Transcript Map, http:// www.ncbi.nlm.nih.gov/SCIENCE96; A New Gene Map of the Human Genome, http://www.ncbi.nlm.nih.gov/ genemap99). Oligonucleotide primer sets, i.e., forward primers labeled with¯uorescence dye Cy-5 (Pharmacia Biotech, Uppsala, Sweden) (kindly provided by Dr. Yusuke Nakamura) and unlabeled reverse primers, were synthesized to amplify the marker DNA sequences.…”
Section: Dna Samples Obtained and Microsatellite Marker Analysismentioning
confidence: 99%
“…DNA samples were subjected to microsatellite marker analysis to know parent-child transmissions of alleles on chromosome 1 as well as on other autosomes. Highly polymorphic microsatellite markers at 102 loci were selected, including 47 dinucleotide and three tetranucleotide repeat markers spanning chromosome 1, and 52 dinucleotide repeats on chromosomes 2-22, according to the maps reported by Bruns et al [1995] and by Dib et al [1996] and those obtained through internet database (Cooperative Human Linkage Center Integrated Maps, CHLC Integrated Maps, http://www.chlc.org; Human Transcript Map, http:// www.ncbi.nlm.nih.gov/SCIENCE96; A New Gene Map of the Human Genome, http://www.ncbi.nlm.nih.gov/ genemap99). Oligonucleotide primer sets, i.e., forward primers labeled with¯uorescence dye Cy-5 (Pharmacia Biotech, Uppsala, Sweden) (kindly provided by Dr. Yusuke Nakamura) and unlabeled reverse primers, were synthesized to amplify the marker DNA sequences.…”
Section: Dna Samples Obtained and Microsatellite Marker Analysismentioning
confidence: 99%
“…18 Moreover, two ras oncogenes, RAB3B locus at 1 p32-31 and RAP1A at 1p13-1p12 on the short arm and a growthtransforming factor gene beta 2 on the long arm of #1 chromosome may very likely be involved in the etiology of osteosarcoma. 19 Similarly, the long arm of #6 chromosome was shown to harbor tumor suppressor genes based on the evidence that in a majority of ovarian tumors, loss of heterozygosity on #6 chromosome is found. 20 The presence of deletions involving chromosome 13 and 17 which harbor RB gene and p53 gene (tumor suppressor genes) has also been implicated in the etiology of osteosarcoma.…”
Section: Osteosarcomamentioning
confidence: 99%
“…1]. In humans, the c-fgr gene is located at chromosome 1 p36.2-p36.1 [2], and genomic clones [3] and human [4][5][6] and murine [7,8] cDNA clones have been isolated. Nucleotide sequence analysis of these clones has shown that c-fgr is a member of a gene family which also includes c-src, fyn, hck, lek, lyn and c-yes [reviewed in ref .…”
Section: Introductionmentioning
confidence: 99%