Report on the clinical effects of inadvertent radiation underdosage in 1045 patients

Ash, D.; Bates, Thelma D.

doi:10.1016/s0936-6555(05)80290-0

Cited by 31 publications

(12 citation statements)

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“…Published lessons from accidental exposures (Ash and Bates, 1994;IAEA, 1998IAEA, , 2000IAEA, , 2001IAEA, , 2002ICRP, 2000ICRP, , 2009NRC, 1988) can be used to check the safety and quality programme to find vulnerable areas in need of improvement. Using lessons from past major events can be called a 'retrospective or reactive approach'.…”

Section: Application Of Lessonsmentioning

confidence: 99%

Tools for risk assessment in radiation therapy

López¹

2012

Ann ICRP

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Radiotherapy has unquestionable benefits, but it is also associated with unique and specific safety issues. It is the only application of radiation in which humans are intentionally delivered very high doses. Safety in radiotherapy remains heavily dependent on human actions. A step-by-step approach is suggested for the prevention of accidental exposures in radiation therapy: (1) allocation of responsibilities to qualified professionals, and design of a quality and safety programme - no radiotherapy practice should be operated without these key elements; (2) use of the lessons from accidental exposures to test whether the quality and safety programme is sufficiently robust against these types of events -publications by the International Commission on Radiological Protection (ICRP) and the International Atomic Energy Agency provide a collection of lessons to facilitate this step; and (3) find other latent risks by posing the questions 'What else could go wrong?' or 'What other potential hazards might be present?' in a systematic, anticipative manner - methods to do so are described briefly in ICRP Publication 112.

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Section: Application Of Lessonsmentioning

confidence: 99%

Tools for risk assessment in radiation therapy

López¹

2012

Ann ICRP

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“…Parmi les 183 malades qui étaient encore vivants un an après leur traitement, plus du tiers présentaient des complications graves du système nerveux central (encéphale et moelle) et du système digestif (Oro-pharynx, colon, rectum). Un résultat inverse a été obtenu entre l'automne 1982 et l'hiver 1991 à l'hôpital de Stokes-Upon-Trent (Royaume-Uni) à cause d'une erreur de calcul dans les nouvelles procédures de traitement : 1045 malades ont reçu des doses inférieures à celles qui leur avaient été prescrites (Ash et Bates, 1994). Les conséquences de cette sous-exposition, de 5 à 35 %, ne pourront jamais être précisées.…”

Section: Victimes En Nombre Importantunclassified

Les accidents d'irradiation, 1950-2000 leçons du passé

Nénot

2001

Radioprotection

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Les accidents causés par les rayonnements ionisants sont rares et possèdent leur propre spécificité. lis ont des effets indirects, particulièrement importants dans les accidents de grande ampleur. La gamme des accidents est large et variée : il existe des accidents qui ne posent pas de problèmes particuliers, des accidents dont la gestion médicale est délicate et des accidents qui mobilisent des moyens très importants. Dans chacune de ces classes on peut distinguer les accidents qui sont diagnostiqués d'emblée et ceux qui sont découverts tardivement et qui auraient pu être ignorés. Certains accidents sont gardés secrets pour des raisons militaires ou politiques. Cette classification permet de tirer un enseignement général, qui devrait contribuer à la prévention et à la gestion des situations accidentelles, tant en ce qui concerne la sûreté que le domaine médical. Radiation accident?: historical review 1950-2000Accidents caused hy ionising radiations are rare and their direct health consequences are specific. The indirect effect? of large-scale accidents are particularly important. The range of radiation accidents is wide and varied: some accidents do not raise any particular question, while the management of some others is tricky, either because of medical prohlems or because of the large size of the accident. In each of these categories, accidents that are immediately diagnosed should he distinguished from those that are recognised only after a certain delay and might have k e n completely ignored. Another category includes the accidents that are kept secret for military or political reasons. Lessons may be derived from such a classification, which should contribute to the prevention and management of accidental situations, with regards to safety and medical handling.

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“…The rapidly increasing degree of complexity has increased the curative potential of radiotherapy, but has also rendered the practice more vulnerable. In addition, the radiotherapy community is aware of the fact that, during the past few years, serious radiological accidents (5)(6)(7)(8) have been reported which could have been avoided, had a comprehensive QA programme been applied (9)(10)(11)(12)(13)(14)(15). The need for a quality assurance programme in radiotherapy has been widely demonstrated (13,16,17).…”

Section: Original Articlementioning

confidence: 99%