Representation of Visual Gravitational Motion in the Human Vestibular Cortex

Indovina, Iole; Maffei, Vincenzo; Bosco, Gianfranco; Zago, Myrka; Macaluso, Emiliano; Lacquaniti, Francesco

doi:10.1126/science.1107961

Cited by 290 publications

(330 citation statements)

References 30 publications

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“…Congruently, epileptic patients with vestibular aurae suffer from lesions surrounding the superior temporal gyrus and the temporoparietal cortex [99,107]. This location has also been confirmed by functional neuroimaging studies in healthy subjects using caloric and galvanic stimulation of the peripheral vestibular system revealing unanimously predominant activations centered on the TPJ and insula [6,19,20,32,39,46,47,50,51,70,72,85,94,95,110,112,118] with activations in the superior temporal gyrus, posterior insula, inferior parietal lobule (angular and supramarginal gyri), and postcentral gyrus. Although many regions surrounding the TPJ/insula have been found activated, opinions concerning the exact location of the human homologue of the PIVC differ (Fig.…”

Section: The Vestibular Cortexmentioning

confidence: 78%

Body ownership and embodiment: Vestibular and multisensory mechanisms

Lopez

Halje

Blanke

2008

Neurophysiologie Clinique/Clinical Neurophysiology

236

163

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Summary Body ownership and embodiment are two fundamental mechanisms of selfconsciousness. The present article reviews neurological data about paroxysmal illusions during which body ownership and embodiment are affected differentially: autoscopic phenomena (out-of-body experience, heautoscopy, autoscopic hallucination, feeling-of-a-presence) and the room tilt illusion. We suggest that autoscopic phenomena and room tilt illusion are related to different types of failures to integrate body-related information (vestibular, proprioceptive and tactile cues) in addition to a mismatch between vestibular and visual references. In these patients, altered body ownership and embodiment has been shown to occur due to pathological activity at the temporoparietal junction and other vestibular-related areas arguing for a key importance of vestibular processing. We also review the possibilities of manipulating body ownership and embodiment in healthy subjects through exposition to weightlessness as well as caloric and galvanic stimulation of the peripheral vestibular apparatus. In healthy subjects, disturbed self-processing might be related to interference of vestibular stimulation with vestibular cortex leading to disintegration of bodily information and altered body ownership and embodiment. We finally propose a differential contribution of the vestibular cortical areas to the different forms of altered body ownership and embodiment. Résumé L'attribution du corps propre et de ses éléments constitutifs (body ownership), ainsi que le sentiment d'incarnation (embodiment) -le fait d'habiter ce corps, d'être localisé dans les limites physiques de ce corps -, sont deux éléments fondamentaux de la conscience de soi. Nous faisons ici la synthèse de données issues de la neurologie montrant que des manifestations paroxystiques telles que les phénomènes autoscopiques (expérience de sortie du corps, héautoscopie, hallucination autoscopique, sensation de présence) et l'illusion de bascule de l'environnement (room tilt illusion) se caractérisent par une atteinte différentielle des mécanismes d'attribution du corps propre et du sentiment d'incarnation. Nous faisons l'hypothèse que les différents phénomènes autoscopiques et l'illusion de bascule de l'environnement se caractérisent par différents patrons de déficits d'intégration des informations sensorielles corporelles (informations visuelles, musculaires proprioceptives et tactiles) combinés à une perte de cohérence entre les références visuelles et vestibulaires. Chez les patients souffrant de phénomènes autoscopiques, les déficits d'attribution du corps propre et du sentiment d'incarnation ont été liés à un dysfonctionnement au niveau de la jonction temporopariétale et d'autres régions corticales recevant des informations vestibulaires, suggérant une contribution importante des afférences vestibulaires dans les mécanismes de la conscience de soi. Nous rapportons également des données de la littérature recueillies chez des sujets sains suggérant la possibilité de manipuler l'attribution ...

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Section: The Vestibular Cortexmentioning

confidence: 78%

Body ownership and embodiment: Vestibular and multisensory mechanisms

Lopez

Halje

Blanke

2008

Neurophysiologie Clinique/Clinical Neurophysiology

236

163

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“…paradigm used to investigate internal models of object trajectories, (e.g. Indovina et al, 2005). The difference between the two button presses was measured (in milliseconds).…”

Section: Mental Ball Droppingmentioning

confidence: 99%

“…Hubbard, 1990) as well as MBD estimation times under different experimental conditions (e.g. Indovina et al, 2005). Furthermore out-of-body experiences, that include mostly a self-elevation in the direction opposite to gravity, have previously been linked to a lack of detection of gravity through disturbed vestibular/otolith processing (e.g.…”

Section: Implicit Self-localizationmentioning

confidence: 99%

Spatial aspects of bodily self-consciousness

Lenggenhager

Mouthon

Blanke

2009

Consciousness and Cognition

181

187

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a b s t r a c tVisual, somatosensory, and perspectival cues normally provide congruent information about where the self is experienced. Separating those cues by virtual reality techniques, recent studies found that self-location was systematically biased to where a visual-tactile event was seen. Here we developed a novel, repeatable and implicit measure of self-location to compare and extend previous protocols. We investigated illusory self-location and associated phenomenological aspects in a lying body position that facilitates clinically observed abnormal self-location (as on out-of-body experiences). The results confirm that the self is located to where touch is seen. This leads to either predictable lowering or elevation of self-localization, and the latter was accompanied by sensations of floating, as during out-of-body experiences. Using a novel measurement we show that the unitary and localized character of the self can be experimentally separated from both the origin of the visual perspective and the location of the seen body, which is compatible with clinical data.

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“…L'étude du mouvement humain permet la caractérisation de ces processus silencieux et inaccessibles. Après deux décennies de recherche sur le mouvement, émerge la théorie computationnelle du contrôle moteur qui permet d'unifier une grande variété de résultats obtenus empiriquement [ Le cas de l'adaptation du mouvement au milieu gravitaire Grâce à de multiples études de neurophysiologie réalisées chez le macaque [2] et chez l'homme [3], un consensus sur l'existence d'un modèle interne de la gravité terrestre dans le cerveau des primates a été trouvé. D'après ce modèle, il est possible de prévoir l'effet permanent de la gravité terrestre sur les mondes animé et inanimé, par exemple la chute d'objets ou la perte d'équilibre.…”

Section: La Théorie Computationnelle Du Contrôle Moteurunclassified