2011
DOI: 10.1016/s0924-9338(11)73074-7
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Representativeness of the patients admitted to psychiatric inpatient units for hypothetical participation in practical clinical trial CATIE

Abstract: IntroductionPharmacological treatment of patients with schizophrenia and other psychoses get scientific backing of its main clinical trials. Methodological guarantees these test tend to strengthen the internal validity of the results at the expense of external validity and the ability to generalize the results to the clinical population. For this reason, and to minimize the shortcomings of external validity while maintaining internal validity, has been promoted in recent years to carry out large clinical trial… Show more

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