Reproducibility of aortic pulse wave velocity as assessed with the new Complior Analyse

Pereira, Telmo; Maldonado, João; Andrade, Ivo; Cardoso, Eva; Laranjeiro, Mafalda; Coutinho, Rita; Conde, Jorge

doi:10.1097/mbp.0000000000000038

Cited by 7 publications

(4 citation statements)

References 28 publications

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“…All measurements were performed by a highly experienced operator, with high reproducibility scores, as previously published [31], and a noteworthy concordance between invasive arterial parameters and the Complior-based pulse wave analysis method, which also been previously documented [32].…”

Section: Endpointsmentioning

confidence: 66%

Effects of a Personalized Physical Exercise Program in the Arterial Stiffness in Older Adults

Pereira¹,

Santos²,

Cipriano³

2019

Artery Res

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This study was aimed at evaluating the effect of a tailored exercise intervention programme in the Arterial Stiffness (AS) of old adults. Methods: Non-randomized intervention study, enrolling 32 community dwelling old adults, aged over 65 years (mean age: 83.28 ± 8.29 years), with no prior history of major cardiovascular events. Participants were divided into two groups (intervention group-Group 2, and control group-Group 1) according to their willingness to participate in the physical training program. The exercise program included aerobic and strength components, prescribed in a personalized approach, and implemented under direct control of two experienced professionals. Aortic Pulse Wave Velocity (PWV), a measure of AS, was evaluated at baseline and 3-months after the intervention period. Clinical evaluation, anthropometric measures and blood samples were also collected in both time-points. Results: The groups had similar clinical and demographic characteristics at baseline. After the intervention program, a significant reduction in PWV was observed only in Group 2 [F(1, 15) = 29.38; p < 0.001; η 2 = 0.67]. A readjustment of the PWV age-dependent trajectory was observed, with a reduction of the absolute PWV in all age strata. A significant reduction in systolic brachial blood pressure was also depicted in Group 2 [mean difference: 12.57 mmHg; F(1, 15) = 9.46; p = 0.01; η 2 = 0.39]. Parameters related to functional status, such as the handgrip strength, the self-efficacy for exercise and the activity and participation profile, were also significantly improved in Group 2. Conclusion: Physical exercise was shown to be an effective non-pharmacological tool to positively modulate age-related decline in AS in older adults.

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Section: Endpointsmentioning

confidence: 66%

Effects of a Personalized Physical Exercise Program in the Arterial Stiffness in Older Adults

Pereira¹,

Santos²,

Cipriano³

2019

Artery Res

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“…In our laboratory, the reproducibility of PWV measurements is excellent and comparable to that in literature. 10 The intraclass correlation coefficient for intraobserver variability was 0.93 (Po0.001), and for interobserver variability was 0.92 (Po0.001) Annual change in PWV was calculated as the absolute difference between PWV at follow-up and baseline, divided by the number of years of follow-up time.…”

Section: Arterial Stiffness Measurementsmentioning

confidence: 99%

Arterial stiffness and decline of renal function in a primary care population

et al. 2016

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Arterial stiffness is an important pathophysiological factor linking cardiovascular disease and kidney disease. Controversy exists as to whether arterial stiffness causes renal function decline, or kidney dysfunction leads to stiffening or whether the association is mutual. We aimed to investigate the longitudinal association between arterial stiffness and annual rate of renal function decline. We prospectively investigated in a primary care population whether carotid-femoral pulse wave velocity (PWV) was associated with estimated glomerular filtration rate (eGFR) and annual decline in eGFR in participants aged ⩾40 years without overt kidney disease. Baseline data on PWV and eGFR were available for 587 participants; follow-up measurements with a mean duration of 5.6 years were available for 222 patients. PWV, female gender and mean arterial pressure were independently associated with eGFR at baseline, although age confounded this association. More importantly, baseline PWV, age and eGFR were independent predictors of renal function decline. Stratification for age showed that the effect of PWV on rate of eGFR decline was amplified with advancing age. On the other hand, baseline eGFR did not determine annual change in PWV, suggesting a unidirectional association between arterial stiffness and eGFR. Arterial stiffness amplifies age-related renal function decline, suggesting that arterial stiffness plays a causal role in the development of renal damage, at least at later stages of age-related renal function decline, possibly through impaired renal autoregulation and increased arterial blood pressure pulsatility.

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“…All measurements were performed by a highly experienced operator, with high reproducibility scores, as previously published [15] , and a noteworthy concordance between invasive arterial parameters and the Complior-based pulse wave analysis method, which also been previously documented [16] .…”

Section: Acute Effects Of Smoking On the Arterial Function Of Young Hmentioning

confidence: 66%

“…Aortic pulse wave velocity and carotid pulse wave analysis Carotid-femoral pulse wave analysis (PWV), a measure of aortic stiffness, and carotid pulse wave analysis (PWA), were assessed simultaneously with the Complior® Analyse device (Alam Medical, Saint-Quentin-Fallavier, France) according to a previously described technique [13,15,16] . The measurements were made with the subjects in supine position with the neck in a slight hyperextension, and slightly rotated to the left, after a resting period of 10 minutes.…”

Section: Acute Effects Of Smoking On the Arterial Function Of Young Hmentioning

confidence: 99%

Acute Effects of Smoking on the Arterial Function of Young Healthy Smokers

Pereira

Costa

2019

Journal of Cardiology and Therapy

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BACKGROUND: Several studies have supported the idea that smoking induces changes with direct impact on endothelial function and arterial stiffness. The main purpose of this study was to assess the acute effects of smoking on vascular function in healthy young adults. METHODS: We designed a quasi-experimental study, including ninety participants aged between 18 and 25 years. Participants were divided into three groups: Active exposure group (AG)-30 usual smokers; passive exposure group (PG) and non-exposure control group (CG), each including 30 non-smokers matched for age, gender and overall lifestyle. Heart rate (HR), brachial blood pressure (bBP), flow-mediated dilation (FMD), aortic pulse wave velocity (PWV) and carotid pulse wave analysis (PWA) were evaluated in two moments: baseline and 30 minutes after smoking exposition (AG and PG) or 30 minutes after the first evaluation (CG). RESULTS: Significant changes from baseline were observed only in the AG, with an increase in PWV, from 5.6 ± 0.7 m/s to 6.1 ± 0.2 m/ s post-smoking (p = 0.040), and a decrease in FMD of about-5.7 ± 2.3% after smoking one cigarette (p < 0.001). A significant increase in brachial and central BP was also observed in the AG. A trend for increase in brachial and central BP, and decrease in the FMD was observed in the PG and no significant changes were depicted in the CG. CONCLUSION: Just one cigarette produces significant detrimental acute effects on the vascular endothelium and hemodynamic profile of healthy young short-term smokers. Changes are also observed, although to a lesser extent, in passive smokers.

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Reproducibility of aortic pulse wave velocity as assessed with the new Complior Analyse

Cited by 7 publications

References 28 publications

Effects of a Personalized Physical Exercise Program in the Arterial Stiffness in Older Adults

Effects of a Personalized Physical Exercise Program in the Arterial Stiffness in Older Adults

Arterial stiffness and decline of renal function in a primary care population

Acute Effects of Smoking on the Arterial Function of Young Healthy Smokers

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