Reproducibility of Arterial Stiffness Indices in Different Vascular Territories and between Different Observers

Симова, Яна; Katova, T.; Kostova, V.; Hristová, Krasimira; Dimitrov, Nikolay

doi:10.1111/j.1540-8175.2010.01365.x

Cited by 4 publications

(2 citation statements)

References 24 publications

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“…DeMarzo (Demarzo, 2009) reported on the value of ICG in detecting subclinical vascular disease in women while we showed that impedance cardiography guided therapy was more effective than standard care in achieving hypertension control in subjects on more than one antihypertensive medication (Smith et al, 2006a). Pulse wave velocity and the augmentation index are now accepted methods for assessment of vascular stiffness (Hitsumoto, 2012; Rabkin et al, 2012; Salmi et al, 2012; Simova et al, 2011; Tomiyama and Yamashina, 2011; Yang et al, 2011; Zhang et al, 2013). The strength of our current research is based in having combined hemodynamic measures with non-invasive indexes of vascular compliance in concert with concomitant measures of hypertension-related biomarkers.…”

Section: Discussionmentioning

confidence: 99%

Hemodynamic and hormonal patterns of untreated essential hypertension in men and women

Ferrario

Jessup

Smith

2013

Therapeutic Advances in Cardiovascular Disease

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Background Knowledge of hemodynamic factors accounting for the development of hypertension should help to tailor therapeutic approaches and improves blood pressure control. Few data exist regarding sex differences of hemodynamic factors contributing to hypertension progression among untreated non-diabetic prehypertensive (PreHyp), Stage I and II subjects as define by the Joint National Commission-7 guidelines (JNC-7). Methods We utilized non-invasive impedance cardiography, applanation tonometry, and plasma measures of angiotensin II, angiotensin-(1-7), serum aldosterone, hs-C reactive protein, and cytokine biomarkers of inflammation to characterize the hemodynamic and hormonal profile of 100 untreated hypertensive subjects (39 females). Results Despite there being no differences between females and males in terms of office blood pressure, heart rate, and body mass index, males demonstrated lower values of pulse pressure, systemic vascular resistance, brachial artery pulse wave velocity, and augmentation index. In each of the three hypertension categories, the increased blood pressure in males was associated with significant augmentations in stroke volume and cardiac output when compared to females. Sex related hemodynamic differences were associated in females with higher plasma levels of leptin, hs-C-reactive protein, plasma angiotensin II, and serum aldosterone and no differences in the serum concentrations of cytokinins. In women but not men, hs-C reactive protein correlated with plasma concentrations of TGF-β1 and body weight, in addition, plasma TGF-β1 correlated with levels of serum VCAM-1. Conclusions The impact of sex differences in the hemodynamic factors accounting for the elevation in arterial pressure in essential hypertensive subjects has been poorly characterized or this information is not available. We suggest that this gap in knowledge may adversely influence choices of drug-treatment since our study shows for the first time significant differences in the hemodynamic and hormonal mechanisms accounting for the increased blood pressure in women compared to men.

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Section: Discussionmentioning

confidence: 99%

Hemodynamic and hormonal patterns of untreated essential hypertension in men and women

Ferrario

Jessup

Smith

2013

Therapeutic Advances in Cardiovascular Disease

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“…(a) Aquisição da imagem para avaliação da rigidez arterial e (b) Onda de pulso aferida na artéria carótida.A pressão local na artéria carótida é tida como uma boa estimativa da pressão central, que é a mesma da aorta ascendente. Foram fornecidos, então, os dados que foram utilizados para a medida da rigidez arterial, aqui representada como velocidade de onda de pulso (VOP), a qual era expressa na tela do equipamento 123. …”

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Estudo da integridade arterial em pacientes com coarctação da aorta, antes e após aortoplastia com implante de stent

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Serial assessment of arterial structure and function in patients with coarctation of the aorta undergoing stenting

Jesus

Assef

Pedra

et al. 2016

Int J Cardiovasc Imaging

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Stenting for CoA has become an acceptable treatment modality in the last 20 years. However little is known about arterial changes after this procedure. To assess arterial structure and function including peripheral reactivity and stiffness and intima-media thickness (IMT) pre and post stenting for coarctation of the aorta (CoA). Twenty-one patients [median age: 15 years (8-39)] were studied at baseline, 1 day, 6 months and 1 year after stenting. Twenty-one healthy subjects (1:1 matched) were used as controls. Left ventricular (LV) mass, ejection fraction, flow-mediated dilation (FMD) and nitrate-mediated dilation (NMD) of left brachial artery, common carotid (CC) and right subclavian artery (RSCA) IMT and pulse wave velocity (PWV) were assessed by echocardiography and vascular ultrasound. CoA patients had higher LV indexed mass (p < 0.0001), impaired FMD (p < 0.0001) and NMD (p < 0.0001), increased PWV (p < 0.0001), carotid and RSCA IMT (both p < 0.0001). All procedures were successful and resulted in significant gradient reduction (p < 0.001). One year after stenting there was improvement in LV function (p = 0.034) and although there was significant reduction of LV mass (103.29 ± 24.77 vs. 74.39 ± 22.07 g/m(2), p < 0.0001) values did not normalize. There was no significant change in FMD, NMD, PWV and CC or RSCA IMT. In patients with CoA, arterial reactivity is impaired and LV mass, arterial stiffness and thickness are increased. Although stenting is successful to relieve the obstruction resulting in better LV function and mass reduction, arterial structure and function remains abnormal after 1 year of follow-up.

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Reproducibility of Arterial Stiffness Indices in Different Vascular Territories and between Different Observers

Abstract: The reproducibility of ET derived AS parameters was good when AS was measured at the common carotid or femoral arteries. On the basis of our results brachial artery is probably not a reliable site for AS measurement.

Cited by 4 publications

References 24 publications

Hemodynamic and hormonal patterns of untreated essential hypertension in men and women

Hemodynamic and hormonal patterns of untreated essential hypertension in men and women

Estudo da integridade arterial em pacientes com coarctação da aorta, antes e após aortoplastia com implante de stent

Serial assessment of arterial structure and function in patients with coarctation of the aorta undergoing stenting

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