Reproducibility of cardiac output measurement by cross sectional and Doppler echocardiography.

Robson, S. C.; Murray, Alan; Peart, Ian; Heads, A.; Hunter, Stewart

doi:10.1136/hrt.59.6.680

Cited by 54 publications

(20 citation statements)

References 16 publications

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“…Indeed, in a recent study comparing high doses (up to 3200 jg) of fenoterol and salbutamol given by spacer in acute severe asthma, no significant arrhythmias were observed with either drug despite significantly greater hypokalaemia and Q-T prolongation with fenoterol. 25 There are several factors which may modify the magnitude of the systemic response to 12 agonists. It is known that regular exposure to 02 agonist results in an attenuated response as a result of receptor downregulation.262' In our study most patients were documented as receiving on-demand P2 agonists, suggesting that subsensitivity had probably not occurred to any great degree.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.

Lipworth

Newnham

Clark

et al. 1995

Thorax

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Results -There was no difference in bronchodilator potency between fenoterol and salbutamol (as median dose ratio): FEV, 1 1 (95% CI 0 4 to 4.6). In contrast, dose ratios for systemic responses showed that fenoterol was more potent than salbutamol: serum potassium 3-7 (95% CI 2-0 to 6.0), tremor 5 7 (95% CI 1-4 to 10.2), heart rate 1-6 (95% CI 10 to 2.3). At a conventional dose of 200 ig the only difference in response between the two drugs was observed for tremor (as mean difference): 0-23 log units (95% CI 0-06 to 0-41 log units). Conclusions -There was no difference in the bronchodilator potency between fenoterol and salbutamol on a microgram equivalent basis. In contrast, systemic potency was greater with fenoterol, although this difference was not clinically relevant at conventional dosages up to 200 pg. (Thorax 1995;50:54-61)

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Section: Discussionmentioning

confidence: 99%

Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.

Lipworth

Newnham

Clark

et al. 1995

Thorax

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“…Doppler measurements of cardiac output were higher than impedance measurements on average by 0.7 li ters-min'1 (SEM 0.4) at baseline, by 0.5 liters-min (SEM 0.5) at 1 pg/kg/min and by 0.6 liters-min-1 (SEM -l general [23,24] and for the ACVF Doppler in particular [12], ACVF Doppler and impedance cardiography pro duced similar within-subject variability which consti tuted only a small proportion (<10%) of the overall variability recorded. The total variability consists of a component owing to differences within subjects, a com ponent owing to differences between subjects and a residual component.…”

Section: Discussionmentioning

confidence: 99%

A Comparison of Attenuation Compensated Volume Flow Based Doppler Echocardiography and Impedance Cardiography in Healthy Volunteers

Broom¹

1990

Am J Noninvas Cardiol

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Attenuation compensated volume flow (ACVF) Doppler echocardiography (dual beam Doppler) measures cardiac output independently of knowledge of aortic cross-sectional area and of angle of insonation. We compared a commercially available ACVF Doppler (Vital Science, Quantascope) with impedance cardiography (BoMed, NCCOM^3) in 8 healthy volunteers. Doppler and impedance readings were made during successive 30-min dobutamine infusions at rates of 1, 2 and 4 pg/kg/min. Dose-related increases were detected by both impedance and Doppler for stroke volume, cardiac output and heart rate. Total variability in the measurement of stroke volume and cardiac output was greater for Doppler than for impedance and the overall coefficient of variation for cardiac output was almost twice as high for Doppler. Within-subject variability for repeated measurements of cardiac output and stroke volume were comparable for Doppler and impedance at all infusion rates with coefficients of variation less than 10%. Component of variance analysis showed that within-subject variability contributed less than 10% to the overall variability of measurements for either technique. The greater overall measurement variability of ACVF Doppler may reflect limitations of the underlying theory or technique and further study of ACVF Doppler is required. However, it may offer no advantage over impedance cardiography for the noninvasive assessment of changes in cardiac function in healthy volunteers.

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“…It is safe, does not cause any discomfort, is reproducible and accurate (9), and has been validated against Fick, dye dilution, thermodilution methods and electromagnetic flow probes (11,14). The aim of this study was to determine the sequence and extent of maternal cardiovascular adaptation to pregnancy in an integrated way in spontaneous and assisted conception pregnancies using Doppler echocardiography.…”

Section: Introductionmentioning

confidence: 99%

A Longitudinal Study of the Maternal Cardiovascular Adaptation to Spontaneous and Assisted Conception Pregnancies

Ogueh

Brookes

Johnson

2009

Hypertension in Pregnancy

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Reproducibility of cardiac output measurement by cross sectional and Doppler echocardiography.

Cited by 54 publications

References 16 publications

Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.

Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.

A Comparison of Attenuation Compensated Volume Flow Based Doppler Echocardiography and Impedance Cardiography in Healthy Volunteers

A Longitudinal Study of the Maternal Cardiovascular Adaptation to Spontaneous and Assisted Conception Pregnancies

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