Reproducibility of current perception threshold with the Neurometer® vs the Stimpod NMS450 peripheral nerve stimulator in healthy volunteers: an observational study

Tsui, Ban C. H.; Shakespeare, Timothy J.; Leung, Danika H.; Tsui, Jeremy H.; Corry, Gareth N.

doi:10.1007/s12630-013-9965-z

Cited by 12 publications

(16 citation statements)

References 26 publications

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“…Furthermore, patients detect thermal stimuli more easily than CPT stimuli. 30,31 Finally, this method is only a semiobjective test in that it requires subjective feedback from patients regarding the detection of electrical stimulation.…”

Section: Discussionmentioning

confidence: 99%

Thermal quantitative sensory testing to assess the sensory effects of three local anesthetic solutions in a randomized trial of interscalene blockade for shoulder surgery

Sermeus

Hans

Schepens

et al. 2015

Can J Anesth/J Can Anesth

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Thermal quantitative sensory testing to assess the sensory effects of three local anesthetic solutions in a randomized trial of interscalene blockade for shoulder surgery Les tests sensoriels quantitatifs thermiques utilisés pour évaluer les effets sensoriels de trois solutions d'anesthésiques locaux dans une étude randomisée de blocs interscaléniques pour les chirurgies de l'épaule Methods This was a prospective randomized trial in patients scheduled for arthroscopic shoulder surgery under general anesthesia and US-ISB. Participants and observers were blinded for the study. We assigned the study participants to one of three groups: 0.5% levobupivacaine 15 mL, 0.5% levobupivacaine 15 mL with 1:200,000 epinephrine, and 0.75% ropivacaine 15 mL. We performed thermal QST within dermatomes C4, C5, C6, and C7 before infiltration and 30 min, six hours, ten hours, and 24 hr after performing the US-ISB. In addition, we used QST, a semi-objective quantitative testing method, to measure the onset, intensity, duration, extent, and functional recovery of the sensory block. We also measured detection thresholds for cold/warm sensations and cold/heat pain. Results Detection thresholds for all thermal sensations within the ipsilateral C4, C5, C6, and C7 dermatomes increased rapidly (indicating the development of a hypoesthetic state) and reached a steady state after 30 min. This lasted for approximately ten hours and returned to normal detection thresholds by 24 hr. There were no differences detected between the three groups at 24 hr

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Section: Discussionmentioning

confidence: 99%

Thermal quantitative sensory testing to assess the sensory effects of three local anesthetic solutions in a randomized trial of interscalene blockade for shoulder surgery

Sermeus

Hans

Schepens

et al. 2015

Can J Anesth/J Can Anesth

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show abstract

“…Indeed, in some studies, they have shown superior performance to CASE IV (sensitivity for DSPN 70% vs. 49% for CASE IV) [101], and have been validated to predict risk of foot ulceration [102]. Current perception thresholds (Neurometer ® ) and contact heat-evoked potentials (CHEPS) are new emerging tools with data on reproducibility and its relationship to more established reference parameters [103][104]. The recently developed normative values for CHEPS may allow for wide adoption in research studies [105].…”

Section: Methods For Assessment Of Small Fiber Neuropathymentioning

confidence: 99%

Distal Sensorimotor Neuropathy: Improvements in Diagnosis

2015

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■ AbstractNeurological complications of diabetes are common, affecting up to 50% of people with diabetes. In these patients, diabetic sensorimotor neuropathy (DSPN) is by far the most frequent complication. Detecting DSPN has traditionally been a clinical exercise that is based on signs and symptoms. However, the appearance of morphometric and neurophysiological techniques along with composite scoring systems and new screening tools has induced a paradigm change in the detection and stratification of DSPN and our understanding of its natural history and etiopathogenesis. These newer techniques have provided further evidence that changes in small nerve fiber structure and function precede large fiber changes in diabetes. Although useful, the challenge for the use of these new techniques will be their sensitivity and specificity when widely adopted and ultimately, their ability to demonstrate improvement when pathogenic mechanisms are corrected. Concurrently, we have also witnessed an emergence of simpler screening tools or methods that are mainly aimed at quicker detection of large fiber neuropathy in the outpatient setting. In this review, we have focused on techniques and tools that receive particular attention in the current literature, their use in research and potential use in the clinical environment.Keywords: diabetic neuropathy · small fiber neuropathy · axon reflex test · nerve conduction · nerve fiber density · laser Doppler imager flare · corneal confocal microscopy · electromyography · sudomotor function

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“…The sensory perception threshold test, which measures the small A delta, A beta, and C fibers is a much better sensory test. These fibers respond to Neurometer stimulation at 5 Hz, 250 Hz, and 2000 Hz and respond to the Stimpod at pulse widths of 0.1 msec, 0.3 msec, 0.5 msec, and 1.0 msec, both at 5 Hz and 2 Hz [22]. Either of these tests should be used to detect sensory nerve damage, in preference to EMG-Nerve conduction velocity studies.…”

Section: Introductionmentioning

confidence: 99%

“…Both thermal and mechanical allodynia need to be present in order to have the diagnosis of reflex sympathetic dystrophy (RSD) [8]. The use of current perception threshold (Neurometer) or Stimpod also has been of great assistance diagnostically to delineate sensory nerve damage, as has thermography [21,22,29].…”

Section: Introductionmentioning

confidence: 99%

Evaluating Chronic Pain Patients Using Methods from Johns Hopkins Hospital Physicians

Hendler¹

2016

J Pain Relief

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Chronic pain patients are misdiagnosed 40%-80% of the time, according to research from Johns Hopkins Hospital physicians. Methods to determine the validity of the complaint of pain, as well as clinical suggestions on methods to improve the accuracy of diagnosis and testing are summarized, as well as the description of an Internet based system which provides diagnoses with a 96% correlation with diagnoses of Johns Hopkins Hospital physicians.

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Reproducibility of current perception threshold with the Neurometer® vs the Stimpod NMS450 peripheral nerve stimulator in healthy volunteers: an observational study

Cited by 12 publications

References 26 publications

Thermal quantitative sensory testing to assess the sensory effects of three local anesthetic solutions in a randomized trial of interscalene blockade for shoulder surgery

Thermal quantitative sensory testing to assess the sensory effects of three local anesthetic solutions in a randomized trial of interscalene blockade for shoulder surgery

Distal Sensorimotor Neuropathy: Improvements in Diagnosis

Evaluating Chronic Pain Patients Using Methods from Johns Hopkins Hospital Physicians

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