Reproducibility of heart rate variability from short-term recordings during five manoeuvres in normal subjects

Carrasco, Susana; Gonzalez, Rosa Maria; Gaitán, M J; Yáñez, Óscar

doi:10.1080/0309190031000111380

Cited by 26 publications

(23 citation statements)

References 20 publications

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“…In one small study, significantly reduced intraCVs were found for LF and HF power for paced breathing (12 breaths/min) compared with spontaneous breathing [19]. However, in that study, indices were not logtransformed, which is surprising in light of the commonly described skewed distribution of HRV indices [22,33,38]. By definition, skewed data results in incorrect and falsely high S.D., which consequently overestimates the variation of the measurements.…”

Section: Hrv Indexmentioning

confidence: 80%

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

et al. 2011

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HRV (heart rate variability) analysis is a widely employed method to assess cardiac autonomic nervous system activity. Accurate HRV measurement is critical to its value as a diagnostic and prognostic tool. Different breathing patterns may affect HRV, but results obtained under static conditions are conflicting. HRV indices decrease considerably during systemic inflammation evoked by experimental endotoxaemia, enabling the determination of the effects of different breathing patterns on HRV in a dynamic setting. We investigated the impact of different breathing patterns on short-term HRV measurements during experimental endotoxaemia. Furthermore, we assessed whether paced breathing improved HRV reproducibility. Twelve healthy male volunteers received an intravenous bolus (2 ng/kg of body weight) of endotoxin [LPS (lipopolysaccharide), derived from Escherichia coli O:113] on two occasions with an interval of 2 weeks. Five-minute HRV recordings were performed just prior to LPS administration and hourly thereafter until 8 h post-LPS. Three breathing protocols were employed every hour: (i) spontaneous breathing, (ii) metronome-guided breathing at the subject's normal respiratory rate ('paced') and (iii) metronome-guided breathing at 150% of the subject's normal respiratory rate ('mild hyperventilation'). LPS administration resulted in a sharp decrease in all of the HRV indices measured, which was similar during both LPS administrations. Neither paced breathing nor mild hyperventilation influenced HRV indices compared with spontaneous breathing. Paced breathing did not improve reproducibility as it did not exert a significant effect on intra-subject coefficients of variation and intra-class correlation coefficients (calculated between both visits). In conclusion, over a wide range of HRV magnitudes during experimental endotoxaemia, neither paced breathing nor mild hyperventilation affected HRV indices. Moreover, paced breathing did not result in a significant improvement in reproducibility. Therefore employing a paced breathing protocol is not required to obtain valid HRV data during endotoxaemia.

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Section: Hrv Indexmentioning

confidence: 80%

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

et al. 2011

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“…In general, the objective of previous works has been to assess the reproducibility of a subset of the HRV metrics used to study a specific patient population or condition of interest. These studies include research on the shortand long-term reproducibility of autonomic measures in supine and standing positions [31], reproducibility of HRV responses to graded lower body negative pressure [20,34], reliability of short-term HRV measures during exercise [3,28,30,62], reproducibility of measures of cardiovascular autonomic nervous function in middle age and elderly subjects [23], reproducibility of frequency domain HRV metrics before and after a standardized meal [18], HRV analysis reproducibility in the chronic phase of myocardial infarction [5], reproducibility of HRV from short-term recording during manoeuvres in normal subjects [9], stability of short recordings in time [54] and reproducibility of HRV metrics obtained from short-term sampling records [21,37]. In addition to the reproducibility of 24 h and 5 min records, assessing the reproducibility of HRV metrics calculated from very short records has significant practical importance [25], since it is not always possible to obtain 5 min records due to instrumentation constraints or study design [17].…”

Section: Resultsmentioning

confidence: 99%

Reliability and accuracy of heart rate variability metrics versus ECG segment duration

2006

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Despite the exponential growth in heart rate variability (HRV) research, the reproducibility and reliability of HRV metrics continues to be debated. We estimated the reliability of 11 metrics calculated from 5 min records. We also compared the accuracy of the HRV metrics calculated from ECG records spanning 10 s to 10 min as compared with the metrics calculated from 5 min records. The mean heart rate was more reproducible and could be more accurately estimated from very short segments (<1 min) than any of the other HRV metrics. HRV metrics that effectively highpass filter the R-R interval series were more reliable than the other metrics and could be more accurately estimated from very short segments. This indicates that most of the HRV is caused by drift and nonstationary effects. Metrics that are sensitive to low frequency components of HRV have poor repeatability and cannot be estimated accurately from short segments (<10 min).

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“…Other researchers indicated that the ICC was suitable for verifying reproducibility because it can measure the association strength among repetitions (Carrasco et al, 2003;Reland et al, 2005). Reproducibility was considered to be "good" if ICC ranged from 0.61 to 0.81 and "almost perfect" if it exceeded 0.81 (Landis et al, 1977).…”

Section: Discussionmentioning

confidence: 99%

The Reproducibility of Cardiovascular Response to a Mental Task

Liu

Iwanaga

Shimomura

et al. 2010

J Physiol Anthropol

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The present study investigated the reproducibility of cardiovascular responses by presenting a mental task to eight healthy subjects four times at intervals of one year and of several days. Subjects performed a mental subtraction task at the same time of day and under the same conditions. For each experiment day, systolic and diastolic blood pressure (SBP and DBP), mean arterial pressure (MAP), cardiac output (CO), heart rate (HR), stroke volume (SV), and total peripheral resistance (TPR) were measured for a 5-minute baseline period, a 5-minute task period, and a 10-minute recovery period. To examine the reproducibility of cardiovascular response, two-way factorial ANOVA (subject factor and experiment day factor) was conducted, and the intra-class correlation coefficient (ICC) was calculated. The results showed that there were no significant differences between experiment days separated by one year or between those separated by several days for all indexes. The ICCs were high for blood pressures (SBP, DBP and MAP, ICCsϾ0.8) and cardiac responses (HR, SV, and CO, ICCsϾ0.7) for both the interval of one year and that of several days. For the total peripheral resistance, ICC was only high at the interval of several days (Ͼ0.7). In conclusion, the reproducibility of the blood pressure response to a mental task was proven, and in case of the changed blood pressure, the cardiac responses were also reproduced for intervals of one year and of several days.

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Reproducibility of heart rate variability from short-term recordings during five manoeuvres in normal subjects

Abstract: In healthy individuals, the temporal and spectral measurements of the heart rate variability from short-term records are stable in a five day period for the manoeuvres studied. Central frequencies of the spectral components might be used as indexes of the autonomic activity.

Cited by 26 publications

References 20 publications

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

Reliability and accuracy of heart rate variability metrics versus ECG segment duration

The Reproducibility of Cardiovascular Response to a Mental Task

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