Reproducibility of left and right ventricular mass measurements with cardiac CT

Schwarz, Florian; Takx, Richard A.P.; Schoepf, U. Joseph; Lee, Yeong Shyan; Ruzsics, Balázs; Gassner, Eva; Chiaramida, Salvatore A.; Henzler, Thomas

doi:10.1016/j.jcct.2011.08.004

Cited by 11 publications

(3 citation statements)

References 29 publications

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“…Schwartz et al, in a study in 2011, evaluated the reproducibility of cardiac CT in measuring left and right ventricular masses. They concluded that cardiac CT scan is signi cantly reproducible and observer-independent [11]. Later on, in 2012, Greupner et al studied the accuracy of cardiac CT in evaluating LVEF and LV wall motion.…”

Section: Discussionmentioning

confidence: 99%

Myocardial demand-supply imbalance: a propensity-matched analysis of normal-range increased left ventricular mass

Shakerian

Rafati

Pouraliakbar

et al. 2022

Preprint

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Purpose: Increased left ventricular myocardial mass index (LVMMI) raises mortality risk due to varied cardiovascular complications, the underlying etiology of which revolves around the decreased left ventricular ejection fraction (LVEF), hence heart failure. We hypothesized that increased LVMMI assessed with cardiac computed tomography (CT), along with increased end-diastolic volume index (EDVI) and interventricular septal wall thickness at diastole (IVSd), were associated with chest discomfort in patients with normal coronary arteries. Methods We retrospectively enrolled 130 patients who had undergone coronary CT angiography in our center between 2018 and 2020. Only normal coronary patients without coexisting medical conditions were recruited in groups with and without chest discomfort. We performed propensity-score matching (PSM) to produce matched groups. Using the previous CT data, we calculated LVMMI, EDVI, and IVSd and compared them between the groups. Results After PSM, the LVMMI was significantly higher in the group with chest discomfort both in the total population and in the females, but not in the males (OR=1.04, 95% CI 1.00-1.08, p-value=0.021 and OR=1.11, 95% CI 1.03-1.19, p-value=0.003, for the total population and the females, respectively). EDVI and IVSd were not significantly different between the groups. Moreover, the receiver operator characteristics (ROC) curve analysis showed a significant diagnostic accuracy of LVMMI in the females for chest discomfort (p-value<0.001). Conclusion We proposed that the increased cardiac CT-derived LVMMI within the normal range, is a potential predictor of chest discomfort due to myocardial demand-supply imbalance, at least in females. Further research is required to establish the results.

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Section: Discussionmentioning

confidence: 99%

Myocardial demand-supply imbalance: a propensity-matched analysis of normal-range increased left ventricular mass

Shakerian

Rafati

Pouraliakbar

et al. 2022

Preprint

View full text Add to dashboard Cite

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“…These differences could be attributed to a greater partial volume effect in the right ventricle due to heavy trabeculations, where more voxels containing both blood and myocardium along the endocardial border may be included in the ventricular cavity (i.e., partial volume effect). While the right ventricular mass is typically calculated at end-diastole [ 7 10 ], based on the results of this study, it is worthwhile to consider the quantification of end-systolic, rather than end-diastolic, right ventricular mass as a clinical standard.…”

Section: Discussionmentioning

confidence: 99%

“…Due to the inaccuracy in echocardiographic measurements of the right ventricular mass, accurate and reproducible quantification has been typically performed using cardiac MRI [ 3 4 5 6 7 8 ] with cardiac CT demonstrating comparable results [ 9 10 11 12 ]. When quantifying right ventricular mass using CT or MRI, the papillary muscles and trabeculations can either be excluded from [ 6 7 8 9 10 11 ] or included in [ 7 8 9 ] the myocardial mass. The previous studies showed that their inclusion increases right ventricular mass by 79% in patients with repaired tetralogy of Fallot [ 7 ], and contributes to a 35% increase in the total right ventricular mass in patients with pulmonary arterial hypertension [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Right Ventricular Mass Quantification Using Cardiac CT and a Semiautomatic Three-Dimensional Hybrid Segmentation Approach: A Pilot Study

Goo

2021

Korean J Radiol

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Objective To evaluate the technical applicability of a semiautomatic three-dimensional (3D) hybrid CT segmentation method for the quantification of right ventricular mass in patients with cardiovascular disease. Materials and Methods Cardiac CT (270 cardiac phases) was used to quantify right ventricular mass using a semiautomatic 3D hybrid segmentation method in 195 patients with cardiovascular disease. Data from 270 cardiac phases were divided into subgroups based on the extent of the segmentation error (no error; ≤ 10% error; > 10% error [technical failure]), defined as discontinuous areas in the right ventricular myocardium. The reproducibility of the right ventricular mass quantification was assessed. In patients with no error or < 10% error, the right ventricular mass was compared and correlated between paired end-systolic and end-diastolic data. The error rate and right ventricular mass were compared based on right ventricular hypertrophy groups. Results The quantification of right ventricular mass was technically applicable in 96.3% (260/270) of CT data, with no error in 54.4% (147/270) and ≤ 10% error in 41.9% (113/270) of cases. Technical failure was observed in 3.7% (10/270) of cases. The reproducibility of the quantification was high (intraclass correlation coefficient = 0.999, p < 0.001). The indexed mass was significantly greater at end-systole than at end-diastole (45.9 ± 22.1 g/m 2 vs. 39.7 ± 20.2 g/m 2 , p < 0.001), and paired values were highly correlated ( r = 0.96, p < 0.001). Fewer errors were observed in severe right ventricular hypertrophy and at the end-systolic phase. The indexed right ventricular mass was significantly higher in severe right ventricular hypertrophy ( p < 0.02), except in the comparison of the end-diastolic data between no hypertrophy and mild hypertrophy groups ( p > 0.1). Conclusion CT quantification of right ventricular mass using a semiautomatic 3D hybrid segmentation is technically applicable with high reproducibility in most patients with cardiovascular disease.

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Technical feasibility of semiautomatic three-dimensional threshold-based cardiac computed tomography quantification of left ventricular mass

Goo

2018

Pediatr Radiol

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Reproducibility of left and right ventricular mass measurements with cardiac CT

Cited by 11 publications

References 29 publications

Myocardial demand-supply imbalance: a propensity-matched analysis of normal-range increased left ventricular mass

Myocardial demand-supply imbalance: a propensity-matched analysis of normal-range increased left ventricular mass

Right Ventricular Mass Quantification Using Cardiac CT and a Semiautomatic Three-Dimensional Hybrid Segmentation Approach: A Pilot Study

Technical feasibility of semiautomatic three-dimensional threshold-based cardiac computed tomography quantification of left ventricular mass

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