Reproducibility of left ventricular blood flow kinetic energy measured by four-dimensional flow CMR

Abstract

Objectives Four-dimensional flow CMR allows for a comprehensive assessment of the blood flow kinetic energy of the ventricles of the heart. In comparison to standard two-dimensional image acquisition, 4D flow CMR is felt to offer superior reproducibility, which is important when repeated examinations may be required. The objective was to evaluate the inter-observer and intra-observer reproducibility of blood flow kinetic energy assessment using 4D flow of the left ventricle in 20 healthy volunteers across two centres in the United Kingdom and the Netherlands. Data description This dataset contains 4D flow CMR blood flow kinetic energy data for 20 healthy volunteers with no known cardiovascular disease. Presented is kinetic energy data for the entire cardiac cycle (global), the systolic and diastolic components, in addition to blood flow kinetic energy for both early and late diastolic filling. This data is available for reuse and would be valuable in supporting other research, such as allowing for larger sample sizes with more statistical power for further analysis of these variables.

Quantifying Myocardial Blood Flow and Resistance Using 4D-Flow Cardiac Magnetic Resonance Imaging

“…Typical 4D fow image parameters were as follows: echo time (TE) of 3.5 s, repetition time (TR) � 10 ms, fip angle of 10 degrees, the FOV 400 × 400 mm, 30 cardiac phases, 40 slices, and VENC of 150 cm/s. Te 4D fow sequence has been described in our previous papers in detail [8][9][10][11]. Average acquisition time for this technique is eight minutes per case [12].…”

Intra-Ventricular Diastolic Hemodynamics under Pharmacological Stress in Patients with Ischemic Heart Disease: Analysis of 4D-Flow and Myocardial Flow Reserve using hybrid13N-ammonia Positron Emission Tomography/Magnetic Resonance

“…In addition, four-dimensional (4D) flow MR imaging has been developed to simulate and quantify blood flow in vivo. Its utility has been initially validated for visualization and quantification of blood flow in great arteries, and the flow analysis using computational fluid dynamics provide novel hemodynamic markers such as the energy loss and the wall share stress [8][9][10] . More recently, several studies have employed 4D flow MR to visualize and quantify intra LV blood flow to assess hemodynamic abnormality associated with various cardiac diseases including cardiomyopathy and structural heart disease, utilizing the quantification of the multi-directional blood stream computed as kinetic energy 11,12 .…”