Reproducibility of Optic Nerve Head Hemoglobin Measures

Abstract

Measurement of ONH Hb levels using the Laguna ONhE program shows high reproducibility both in glaucomatous and nonglaucomatous ONHs.

Glaucoma diagnostic capacity of optic nerve head haemoglobin measures compared with spectral domain OCT and HRT III confocal tomography

“…The method also shows excellent intraobserver, interobserver, within‐session and between‐session reproducibility in pseudophakic patients with and without glaucoma along with high interanalysis reproducibility when performed by a masked examiner (Mendez‐Hernandez et al. ).…”

Preliminary Study of the Differences in Optic Nerve Head Hemoglobin Measures Between Patients With and Without Childhood Glaucoma

“…The good reliability of this new method has been demonstrated and it seems easy to implement in routine clinical practice. 18 The method used in this study may be applied in all clinical centers because only a good photograph of optic nerve is necessary for image process- ing with the Laguna ONhE software. The cooperation required is reached in almost every patient, even the youngest of patients, because only a fundus picture using retinography is required.…”

“…The strategy used by the Laguna ONhE software has been described in detail previously. 18 The final result of dividing the papilla with two concentric rings and eight 45-degree radial sectors was a figure with 24 sectors (Figure 1). We also obtained the hemoglobin levels across the vertical disc diameter (sectors 8 and 20) because it is widely known that glaucomatous damage principally af-fects this area of the optic nerve head.…”

“…16,17 The main advantage of the Laguna OnhE software is that it is a non-invasive method that is easy to perform and provides quality hemoglobin measurements. 18 In fact, a fundus retinography is usually performed as a regular clinical assessment in patients with glaucoma. Therefore, it is also an inexpensive tool because no further examination would be required.…”

Relationship between Retinal Nerve Fiber Layer Thickness and Hemoglobin Present in the Optic Nerve Head in Glaucoma

“…After a first multicenter study demonstrating the usefulness of the procedure, we analyzed its reproducibility [9], and it was then applied to ocular hypertensives [10]. New studies have allowed separating the rim from cup information, analyzing images obtained with a stereoscopic camera [11], and also associating two-dimensional photographic images with optical disk and cup delimitations provided by OCT [12].…”