Reproducibility of the Heidelberg Retina Tomograph III Glaucoma Probability Score

Abstract

GPS is a highly reproducible diagnostic tool, especially in the case of "good" or better quality images as evaluated by the HRT software; moreover, the reproducibility of the GPS parameters was significantly better in normal subjects than in glaucoma patients.

GDx Staging System

“…15,16 This method is currently used in many ophthalmic centers, both for clinical and research purposes. [22][23][24][25][26] The aim of this study was to use a similar procedure to classify RNFL loss severity based on GDx VCC parameters.…”

Repeatability of Heidelberg Retinal Tomography 3 and effect of alignment algorithm on glaucoma suspects

“…Clinically, imaging instruments such as the HRT are often used to screen a broad clinical group of glaucoma suspects, which includes patients with suspect optic nerve head, visual field results or historical risk factors for developing glaucoma regardless of intraocular pressure (IOP), as normal tension glaucoma with normal IOP is common among many populations . Furthermore, while it is known that individual sectors may be better predictors of glaucoma than global parameters, only two studies explore sectoral repeatability for the MRA and one for the GPS . In addition, the effect of the new image registration module on repeatability has not been fully explored …”

“…26,27 Currently, there are limited investigations on the repeatability of the MRA or the GPS module for the HRT3 with version 3 analysis software. Previous studies have shown the repeatability of the MRA and GPS module on the HRT3 to be high; however, applicability of these studies to general clinical practice is limited due to the small sample size and analysis of specific disease cohorts (such as established glaucoma cohorts, [28][29][30] ocular hypertensive patients 31,32 or normal subjects 33,34 ). Clinically, imaging instruments such as the HRT are often used to screen a broad clinical group of glaucoma suspects, which includes patients with suspect optic nerve head, visual field results or historical risk factors for developing glaucoma regardless of intraocular pressure (IOP), as normal tension glaucoma with normal IOP is common among many populations.…”

“…[35][36][37] Furthermore, while it is known that individual sectors may be better predictors of glaucoma than global parameters, [14][15][16]20 only two studies explore sectoral repeatability for the MRA 31,33 and one for the GPS. 34 In addition, the effect of the new image registration module on repeatability has not been fully explored. 25 The aim of this study was to examine the short-term repeatability of the HRT3 with MRA and GPS algorithms and the effect of the new image registration module on a glaucoma suspect population both globally and sectorally.…”

Einfluss der Vorderkammertiefe auf die Vermessung des Sehnervenkopfs mit OCT und HRT 3

“…Mit der Einführung der Laser-Scanning-Ophthalmoskopie (HRT) und der optischen Kohärenz-Tomografie (OCT) wurde dieser Einfluss minimiert. Sowohl die konfokale Laser-Scanning-Methode des HRT 3 als auch die optische Kohärenztomografie des OCT liefern reproduzierbare Messungen der Papillentopographie [2][3][4][5][6][7][8][9][10][11][12]. Allerdings haben optische Eigenschaften des brechenden Mediums Auge einen Einfluss auf diese bildgebenden Verfahren [13][14][15][16][17].…”