Reproductive outcome following hysteroscopic myomectomy in patients with infertility and recurrent abortions

Roy, Kallol Kumar; Singla, Sham; Baruah, Jinee; Sharma, Jai Bhagwan; Kumar, Sunesh; Singh, Neeta

doi:10.1007/s00404-010-1531-0

Cited by 50 publications

(34 citation statements)

References 29 publications

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“…Three studies [26,30,35] have already been analyzed in the other ''Results'' sub-sessions. Finally, Roy et al in 2010 retrospectively analyzed two-months second-look hysteroscopies in 186 patients with infertility and recurrent abortions who had undergone resectoscopic myomectomy, showing IUA formation in only 2 patients (1.07%) [38]. All patients in this study had received intraand post-operative antibiotic prophylaxis, as well as a course of estradiol valerate (2 mg per day) lasting 30 days.…”

Section: Antibiotic Administrationmentioning

confidence: 95%

“…We identified 8 studies evaluating the role of hormonal therapy in preventing IUA [22,23,26,27,30,31,38,39]. Seven studies [22,23,26,27,30,31,38] have already been analyzed in the other ''Results'' sub-sessions.…”

Section: Post-operative Hormonal Therapymentioning

confidence: 98%

“…In our search, we identified 4 studies evaluating antibiotic therapy for preventing postoperative IUA [26,30,35,38]. Three studies [26,30,35] have already been analyzed in the other ''Results'' sub-sessions.…”

Section: Antibiotic Administrationmentioning

confidence: 99%

“…Seven studies [22,23,26,27,30,31,38] have already been analyzed in the other ''Results'' sub-sessions. Roy et al [38] in a prospective randomized study evaluated the efficacy of estrogen in preventing IUA following hysteroscopic septal resection. Enrolled patients were randomized to receive 2 mg estradiol valerate (group A) or 5 mg folic acid (group B) for 30 days after hysteroscopic septal resection.…”

Section: Post-operative Hormonal Therapymentioning

confidence: 99%

See 3 more Smart Citations

Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review

Sardo

Calagna

Scognamiglio

et al. 2016

European Journal of Obstetrics & Gynecology and Reproductiv

121

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Section: Antibiotic Administrationmentioning

confidence: 95%

Section: Post-operative Hormonal Therapymentioning

confidence: 98%

Section: Antibiotic Administrationmentioning

confidence: 99%

Section: Post-operative Hormonal Therapymentioning

confidence: 99%

See 2 more Smart Citations

Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review

Sardo

Calagna

Scognamiglio

et al. 2016

European Journal of Obstetrics & Gynecology and Reproductiv

121

View full text Add to dashboard Cite

“…Therefore, it is worth exploring whether uterine fibroids affect IVF-ET pregnancy outcomes and whether myomectomy should be carried out before IVF-ET [13]. Submucosal uterine fibroids can significantly decrease the implantation rate and the clinical pregnancy rate [14], and the removal of submucosal uterine fibroids can markedly improve pregnancy outcomes after assisted reproductive technology [15,16]. Subserosal uterine fibroids have few adverse effects on the outcomes of IVF-ET, so their removal is not required before IVF-ET [3,16,17].…”

Section: Discussionmentioning

confidence: 99%

Effects of the Distance between Small Intramural Uterine Fibroids and the Endometrium on the Pregnancy Outcomes of in Vitro Fertilization-Embryo Transfer

Wang

et al. 2014

Gynecol Obstet Invest

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Aim: To explore the effects of the distance between small intramural uterine fibroids (≤4 cm) and the endometrium on the outcomes of in vitro fertilization-embryo transfer (IVF-ET). Methods: We prospectively analyzed pregnancy outcomes in 117 infertile women with small intramural uterine fibroids and 117 infertile women without uterine fibroids who all underwent IVF-ET. The size and number of small intramural uterine fibroids and the shortest distance between the small intramural uterine fibroids and the endometrium were measured by transvaginal three-dimensional ultrasound. The endometrial and subendometrial blood flow parameters, implantation rate, clinical pregnancy rate, abortion rate and live birth rate were compared between the women with and without small uterine fibroids and among the different shortest distances (≤1, 1-3 and >3 mm). The effects of the size and number of small intramural uterine fibroids on IVF-ET outcomes were observed. Results: The endometrial volume on ET day, the implantation rate and the live birth rate were significantly lower, but the abortion rate was significantly higher, in the women with small intramural uterine fibroids than in those without uterine fibroids (p < 0.05). The endometrial flow index was higher in the shortest distance ≤1-mm group than in the groups with 1-3 and >3 mm, and the implantation rate was higher in ≤1-mm group than in the >3-mm group (p < 0.05). There were no significant differences in clinical outcomes between different sizes and numbers of small intramural uterine fibroids. Conclusion: Small intramural uterine fibroids can affect IVF-ET outcomes. Compared with other shortest distances (1-3 and >3 mm), the shortest distance of ≤1 mm has a higher implantation rate.

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Differences in the anatomical structure of the uterus between fertile and infertile individuals

et al. 2023

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Infertility affects a significant portion of the reproductive population and is caused by structural and hormonal factors. The prevalence of congenital uterine anomalies is 3%-4%, with the most common anomaly being septate uterus. However, further research is needed to determine whether these anomalies can cause infertility. In this study, we compared the morphometric parameters of the uterus of fertile and infertile individuals. Based on the data obtained, we aimed to determine the parameters to be evaluated for fertility prediction and to investigate the effect of uterine septum on fertility. The uteruses of 55 infertile and 80 fertile individuals between the age range of 20-45 years were analyzed retrospectively using magnetic resonance images. Infertile individuals were categorized into two groups according to the reasons for infertility: Group I, which included women with congenital uterine anomalies (septate uterus), and Group II, which included women with tubal and male factors. Group III comprised fertile individuals. Uterine length (UL), uterine body length (UbL), cervical length (CxL), uterine cavity length (UcL), anteroposterior diameter (APD), transverse diameter (TD), fundal thickness (FT), and ostial distance (OD) were measured. The uterine positions were examined. The data of uterine variables were evaluated statistically according to age and groups. The mean ages of individuals in

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Reproductive outcome following hysteroscopic myomectomy in patients with infertility and recurrent abortions

Abstract: Hysteroscopic myomectomy is a safe and effective method for improving the obstetric outcome in women with infertility and recurrent abortions and associated submucous fibroids.

Cited by 50 publications

References 29 publications

Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review

Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review

Effects of the Distance between Small Intramural Uterine Fibroids and the Endometrium on the Pregnancy Outcomes of in Vitro Fertilization-Embryo Transfer

Differences in the anatomical structure of the uterus between fertile and infertile individuals

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