Reproductive Risk Factors for Thyroid Cancer: A Prospective Cohort Study in Khon Kaen, Thailand

Sungwalee, Wararat; Vatanasapt, Patravoot; Kamsa-ard, Siriporn; Suwanrungruang, Krittika; Promthet, Supannee

doi:10.7314/apjcp.2013.14.9.5153

Cited by 31 publications

(21 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite two case-control studies performed in China (Preston-Martin et al, 1993) and New-Caledonia (Truong et al, 2005) evidenced, as we did, an increased risk in women who were everpregnant, two cohort studies, performed in China (Wong et al, 2006) and Japan (Pham et al, 2009), did not evidence such an increased risk, and another performed in Thailand, although based on 17 cases showed a decreased risk (Sungwalee et al, 2013). Results in other populations are heterogeneous (Peterson et al, 2012) and this heterogeneity does not seem to be attributable only to differences in number of children between studied populations.…”

Section: Discussioncontrasting

confidence: 79%

Differentiated Thyroid Carcinoma Risk Factors in French Polynesia

Xhaard¹,

Ren²,

Cléro³

et al. 2014

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 79%

Differentiated Thyroid Carcinoma Risk Factors in French Polynesia

Xhaard¹,

Ren²,

Cléro³

et al. 2014

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

“…Concerning age at menarche and DTC risk, most studies reported no significant associations, whereas other showed either early (<12 years) (16, 20, 29) or late (>15–16 years) (13, 16, 18, 27) age at menarche to be weakly associated with increased DTC risk. A history of irregular menstrual cycles has been reported to confer a higher risk of DTC, the magnitude of the observed associations being generally weak and/or limited to specific subsets of population (18, 27).…”

Section: Resultsmentioning

confidence: 96%

Female Reproductive Factors and Differentiated Thyroid Cancer

et al. 2017

View full text Add to dashboard Cite

Differentiated thyroid cancer (DTC) is markedly more common in women than men, the highest female-to-male ratio being recorded during the reproductive period. This evidence has led to the suggestion that female hormonal and reproductive factors may account for the observed DTC gender disparity. This review focuses on current evidence on the risk of DTC in conjunction with major female reproductive factors, including the impact of pregnancy on DTC occurrence and progression/recurrence. Overall, studies exploring the link between the risk of DTC and menstrual and menopausal factors, oral contraceptives and/or hormone replacement therapy, showed these associations, if any, to be generally weak. Nonetheless, there is some evidence that higher levels of exposure to estrogens during reproductive years may confer an increased risk of DTC. As far as pregnancy is concerned, it is unclear whether a potential association between parity and risk of DTC actually exists, and whether it is enhanced in the short-term following delivery. A possible role for pregnancy-related factors in DTC progression has been recently suggested by some reports, the results of which are consistent with a worse outcome in the short-term of women diagnosed with DTC during gestation compared to non-pregnant control patients. Also, some progression of disease has been described in women with structural evidence of disease prior to pregnancy. However, there seems to be no impact from pregnancy in DTC-related death or overall survival. Several in vitro and animal studies have evaluated the influence of estrogens (E) and estrogen receptors (ERs) on thyroid cell proliferation. Presently available data are indicative of a role of E and ERs in thyroid cancer growth, although considerable discrepancies in respect to ER expression patterns in thyroid cancer tissues actually exist. Further studies providing more direct evidence on the possible role of E and of placental hormones and growth factors on thyroid growth may expand our knowledge on the mechanisms beyond the gender disparity of proliferative thyroid diseases.

show abstract

“…Finally, 24 studies met the inclusion criteria, including 7 cohort studies [12–14, 16, 17, 32, 33] and 17 case-control studies [18–20, 34–47] (Supplementary Figure S1). The detailed characteristics of these studies were shown in Table 1 and Table 2.…”

Section: Resultsmentioning

confidence: 99%

A meta-analysis of alcohol consumption and thyroid cancer risk

Wang

Cheng

et al. 2016

Oncotarget

View full text Add to dashboard Cite

BackgroundIt is still inconclusive whether alcohol consumption affects the risk of thyroid cancer. We conducted a meta-analysis of available epidemiological data to address this issue.ResultsCompared with nondrinkers, the pooled relative risks (RRs) and corresponding 95% confidential intervals (CIs) of thyroid cancer were 0.80 (95% CI 0.71-0.90) for any drinkers, 0.81 (95% CI 0.70-0.93) for light and 0.71 (95% CI 0.63-0.79) for moderate drinkers. The dose–response analysis suggested that there is no evidence of a dose-risk relationship between alcohol intaking and thyroid cancer risk (P = 0.112).MethodsEligible studies were identified by searching PubMed and EMbase databases. A total of 24 studies, included 9,990 cases with thyroid cancer, were included in this meta-analysis. We defined light alcohol intake as ≤ one drink/day and moderate as >one drink/day. The summary risk estimates were calculated by the random effects model. A dose-response analysis was also conducted for modeling the dose-risk relation.ConclusionThis meta-analysis confirmed an inverse association between alcohol consumption and thyroid cancer risk. Further studies are needed to better understand the potential mechanisms underlying this association.

show abstract

Reproductive Risk Factors for Thyroid Cancer: A Prospective Cohort Study in Khon Kaen, Thailand

Cited by 31 publications

References 11 publications

Differentiated Thyroid Carcinoma Risk Factors in French Polynesia

Differentiated Thyroid Carcinoma Risk Factors in French Polynesia

Female Reproductive Factors and Differentiated Thyroid Cancer

A meta-analysis of alcohol consumption and thyroid cancer risk

Contact Info

Product

Resources

About