2023
DOI: 10.1021/acs.molpharmaceut.2c00934
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Reproductive Toxicity Evaluation of Graphene-Based Tumor Cell Nucleus-Targeting Fluorescent Nanoprobes on Reproduction and Offspring Health

Abstract: A new graphene-based fluorescent nanoprobe for tumor cell nucleus (GTTNs) was synthesized in our laboratory that penetrates the cell membrane and particularly targets cancer cell nucleus and displays tremendous potential for clinical applications. Although acute and subacute toxicity studies have been conducted on GTTNs, a primary result could be drawn that GTTNs appear to have almost no acute and subacute toxicity. However, as an important part of safety evaluation, the influences on reproductive and offsprin… Show more

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Cited by 2 publications
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“…Therefore, the contact impedance on the skin is several orders of magnitude higher than that of Ag/AgCl gel electrodes, leading to a unsatisfactory SNR. There is also concern about the toxicity of the nanofillers [17][18][19] .…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, the contact impedance on the skin is several orders of magnitude higher than that of Ag/AgCl gel electrodes, leading to a unsatisfactory SNR. There is also concern about the toxicity of the nanofillers [17][18][19] .…”
Section: Introductionmentioning
confidence: 99%