Repurposing FDA approved drugs against monkeypox virus DNA dependent RNA polymerase: virtual screening, normal mode analysis and molecular dynamics simulation studies

Khan, Ahmad Abdul Salam; Yousaf, Muhammad Abrar; Azhar, Jahanzaib; Maqbool, Muhammad Faisal; Bibi, Ruqia

doi:10.1007/s13337-024-00869-8

VirusDis.

2024

DOI: 10.1007/s13337-024-00869-8

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Repurposing FDA approved drugs against monkeypox virus DNA dependent RNA polymerase: virtual screening, normal mode analysis and molecular dynamics simulation studies

Ahmad Abdul Salam Khan,

Muhammad Abrar Yousaf,

Jahanzaib Azhar

et al.

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Exploring the Knowledge and Attitude of Medical and Allied Health Sciences Students towards Monkey Pox Virus

Lasi,

Yawer,

Sabir

et al. 2024

AMRJ

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Background: Human Monkey Pox (HMPX) is a zoonotic disease caused by the pathogenic agent Monkeypox Virus (MPXV) and remains a global health burden. After Africa, its outbreak has been reported in America, Europe, and a few other regions of Africa. While quite a few cases were also reported in Pakistan. Although it is a self-limiting disease, it remains a potential threat to the human population, with an increasing morbidity rate and case fatality rate. Methods: In a cross-sectional study conducted from September to December 2022, the aim was to assess the knowledge and attitudes of medical and allied health students regarding Mpox. Three hundred students from various medical and allied health departments at Hamdard University of Karachi participated in the study using convenience sampling. They were given an electronic questionnaire to gather their responses. Results: The findings showed that participants had an average knowledge of (Χ2=1.080, p>0.05). Many participants showed positive attitudes towards disease (Χ2=67.22, p<0.001). Based on gender, the knowledge of male participants was better (Χ2=17.32, p < 0.01), whereas attitude was positive in both genders (Χ2=24.87, p<0.01). MBBS and Pharm D students demonstrated average knowledge (Χ2=81.058, p < 0.01) while DPT students showed positive attitudes toward Mpox. Conclusion: Knowledge regarding emerging pandemics needs to be improved in students of health professions. Thus, a more focused learning attitude is crucial to developing a futuristic professional attitude. Keywords: Healthcare, Knowledge, Monkeypox, Pandemic.

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Exploring the Knowledge and Attitude of Medical and Allied Health Sciences Students towards Monkey Pox Virus

Lasi,

Yawer,

Sabir

et al. 2024

AMRJ

View full text Add to dashboard Cite

show abstract

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Repurposing FDA approved drugs against monkeypox virus DNA dependent RNA polymerase: virtual screening, normal mode analysis and molecular dynamics simulation studies

Cited by 1 publication

References 45 publications

Exploring the Knowledge and Attitude of Medical and Allied Health Sciences Students towards Monkey Pox Virus

Exploring the Knowledge and Attitude of Medical and Allied Health Sciences Students towards Monkey Pox Virus

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