Requiem for trichloroethylene?

Atkinson, Ruth; Beynon, D.; Birt, R.C.; Cameron, A. E.; Lee, J. Alfred; Rushman, G. B.; Thorne, Tracey; Watt, Man-Joe

doi:10.1111/j.1365-2044.1979.tb08548.x

Cited by 4 publications

(4 citation statements)

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“…The main advantage of cryoanesthesia is that, unlike other topical anesthetics and analgesics, it operates on all cells, rather than just nerve cells, resulting in instantaneous anesthesia [ 20 ]. Although the anesthesia created by cryoanesthesia only lasts for 2–5 seconds, it is effective in reducing pain associated with needle insertion [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of cryoanesthesia and sweet tasting solution in reducing injection pain in pediatric patients aged 7–10 years: a randomized controlled trial

Davangere Padmanabh,

Gangurde,

Jhamb

et al. 2024

J Dent Anesth Pain Med

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Background The delivery of profound local anesthetics helps children receive successful treatment by reducing fear, anxiety, and discomfort during dental procedures. Local anesthetic injections are the most anticipated stimuli in dental surgery. Children's perceptions of pain can be altered by applying cryotherapy to precool the oral mucosa or by diverting their minds through taste distractions before administering local anesthetic injections. This study aimed to evaluate the efficacy of cryoanesthesia and xylitol sweet-tasting solution at the injection site in 7–10-year-old children. Methods A total of 42 participants, aged 7–10 years, who underwent dental treatment requiring local anesthesia, were enrolled in the study. The children were randomly divided into three groups. In group I, sterile water was held in the mouth for 2 minutes before anesthetic administration, similar to group II, and in group III, a xylitol sweet-tasting solution was used for 2 minutes before needle insertion. The analysis of pain perception was carried out based on the Visual Analog Scale (VAS) and the Sound, Eyes, and Motor (SEM) scale. For VAS analysis, a one-way analysis of variance (ANOVA) was performed for intergroup comparison, and a post hoc Tukey test was performed for subgroup analysis. For the categorical SEM scale, the Kruskal–Wallis test followed by the post hoc test was performed for intergroup comparison. Where a P value of <0.05 was considered statistically significant at 95% confidence intervals. Results Cryoanesthesia significantly reduced pain scores on VAS (4.21 ± 1.42) when compared to those on VAS with xylitol sweet-tasting solution (5.50 ± 1.40) and that with sterile water (6.14 ± 2.47). Intergroup comparison of the VAS scores among the three groups was performed using one-way ANOVA, which demonstrated statistically significant differences (P value <0.026) on the VAS scale. Intergroup comparison of the SEM scale was performed using the Kruskal–Wallis test, followed by post hoc comparison, which exhibited statistically significant differences (P < 0.007) among the three groups for the SEM scale. Conclusion Cryoanesthesia demonstrated higher efficacy in reducing injection pain than that exhibited by the xylitol sweet-tasting solution.

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Section: Discussionmentioning

confidence: 99%

Effect of cryoanesthesia and sweet tasting solution in reducing injection pain in pediatric patients aged 7–10 years: a randomized controlled trial

Davangere Padmanabh,

Gangurde,

Jhamb

et al. 2024

J Dent Anesth Pain Med

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“…Therefore, those with significant renal excretion should be avoided or used in reduced doses, and more extensive monitoring of their actions should be carried out. Of the muscle relaxants, over 80 per cent of the non‐depolarising muscle relaxant gallamine is excreted renally 16 and only the new agent attracurium is not dependent on renal elimination to some extent (it relies on Hofmann elimination at body temperature and pH).…”

Section: Urea and Electrolytesmentioning

confidence: 99%

Pre‐operative investigations — the anaesthetist's perspective

McCleane¹

1990

Int J Clinical Practice

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“…Gazların monitörizasyonunun anestezide uygulamaya girmesi ise taze gaz akımı 2 L/dk veya daha düşük kullanılabilme olanağını doğurmuştur. Ayrıca ekspire edilen gazların, atılmayıp karbondioksitin eliminasyonundan sonra tekrar hastaya verilebileceği bildiril mektedir (6).…”

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“…Halotanın ise klinik dozlarda 2 saat süre ile uygulanması hastada lipid peroksidasyonu oluşturmakta ve vücuttan metabolitlerinin atılması ise 3 hafta gibi uzun bir süreyi kapsadığı bildirilmektedir (6). Bu da hasta için istenmeyen bir durum oluşturmaktadır.…”

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Clinlcal evaluation of the low-flow enflurane anaesthesia

Göksu,

Çeliköz,

Koçoğlu

et al. 2000

Eur J Ther

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The purpose of this study is to compare clinical effects of the low-flow anaesthesia, a technique recently gained popularity, with the high-flow anaesthesia by using the volatil anaesthetic, enflurane. Sixty patients whose ages ranged from 20 to 53 years, were included in the study. There were 38 female and 22 male patients. The patients were randomly divided into two groups. Low-flow enflurane anaesthesia was used in 30 patients who constituted the first group, and included in the second group is the remaining 30 patients who were administered high- flow enflurane anaesthesia. Heart rate, systolic-diastolic and mean arterial pressures, body temperature, peripheral oxygen saturation (SpO2), tidal volume, respiratory rate, end tidal CO2, inspired oxygen, inspired N2O, inspired volatile anaesthetic concentrations, %vapo- riser/%inspired volatile anaesthetic concentration, and airway pressure of the patients were monitored and evaluated every five minute. Recovery time and early postanaesthetic complications of the groups were compared clinically. Hemodynamic parameters, SpO2, and body temperature of the groups were not significantly different (p>0.05). in conclusion low-flow anaesthesia is advan- tageous when compared to the conventional high-flow anaesthesia, and can be used routinely if the appro- priate monitorisation set-up exists.

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Requiem for trichloroethylene?

Cited by 4 publications

References 0 publications

Effect of cryoanesthesia and sweet tasting solution in reducing injection pain in pediatric patients aged 7–10 years: a randomized controlled trial

Effect of cryoanesthesia and sweet tasting solution in reducing injection pain in pediatric patients aged 7–10 years: a randomized controlled trial

Pre‐operative investigations — the anaesthetist's perspective

Clinlcal evaluation of the low-flow enflurane anaesthesia

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