Research ethical committees in Scotland.

Recent experience of ethics committee review of a multicentre research project.

“…Surveys have shown wide variation in constitution of committees (Allen & Waters, 1982;Allen et al, 1983;British Medical Association, 1981) and have highlighted surprising differences in their working practices (Thompson et al, 1981). Recent experience has confirmed this.…”

Understanding the structure and practices of research ethics committees through research and audit: a study from Mexico

“…The weaknesses of the IMSS committees are not substantially different from those reported from committees in other countries which report difficulties in terms of their composition [5,8,9], mode of operation [5][6][7][8][9][10]58,59], and potential conflicts of interest [26,53,57,60]. Claims for standardised procedures [7][8][9]60,61], training [5,10,57,60], and the implementation of audit practices [7,10,38,57,58,61] to improve the LRECs workings are found in literature worldwide.…”

“…Claims for standardised procedures [7][8][9]60,61], training [5,10,57,60], and the implementation of audit practices [7,10,38,57,58,61] to improve the LRECs workings are found in literature worldwide. But is it standardisation that is needed or rather a better understanding of how committees work in relation to the guidelines and regulations that already exist.…”

“…The fascinating world of LRECs is comparatively under-researched, although there are increasing numbers of international publications that address a variety of the facets of committees including: structure, process, monitoring, regulation and training [5][6][7][8][9][10]. The role of LRECs for many is a mystery, and there are expressed concerns that the increasing guidelines, regulations and bureaucracy being created through the development of LRECs is not improving the overall purpose of these committees which is to protect human subjects [10][11][12][13].…”

Adult polycystic kidney disease.

“…Tuberculosis preceded the conditions that make up AIDS' by a median of two months, and similar findings have been reported from other studies.68 HIV infection is a cofactor with one ofthe highest risk ratios for the development of tuberculosis in people already infected with Mycobacterium tuberculosis. 9 Strong evidence that in people infected with HIV tuberculosis develops from the reactivation of a latent tuberculous infection comes from a follow up study of a cohort of injecting drug users whose tuberculin and HIV state was known. '0 Some 14% of those seropositive for HIV and with prior tuberculin sensitivity developed tuberculosis compared with only 0 3% ofthose seropositive for HIV but without tuberculin sensitivity.…”