Global health research reflects and can either perpetuate or challenge the complex power hierarchies and inequities that characterize our systems for health and the societies in which they are situated. The imperative to embed equity in health research aligns with broader efforts globally to promote equitable partnerships among researchers, and between researchers and the communities potentially impacted by their research, or with whom knowledge is co-produced. We describe lessons learnt from piloting a heuristic and diagnostic tool for researchers to assess integration of equity considerations into their research practices. The ‘8Quity’ tool comprises eight domains of equity we developed which roughly correspond to the typical stages in the research process—from team formation to capacity-strengthening, research ethics and governance to relationships with research partners, participants, and stakeholders beyond the project period. Resources that detail how this may be done on a practical level are also shared, corresponding to each of the eight domains. We acknowledge that tools like 8Quity may be helpful, even necessary, but are insufficient for the broader societal change required to ensure equity in the research enterprise. However, by firmly setting intentions and accountabilities within our research practices, we can (as researchers) play a role, however modest, in turning the tide of the injustices that leave some communities behind.