Research of electrosurgical unit with novel antiadhesion composite thin film for tumor ablation: Microstructural characteristics, thermal conduction properties, and biological behaviors

Abstract

The objective of this study was to use surface functionalization to evaluate the antiadhesion property and thermal injury effects on the liver when using a novel electrosurgical unit with nanostructured-doped diamond-like carbon (DLC-Cu) thin films for tumor ablations. The physical and chemical properties of DLC-Cu thin films were characterized by contact angle goniometer, scanning electron microscope, and transmission electron microscope. Three-dimensional (3D) hepatic models were reconstructed using magnetic resonance imaging to simulate a clinical electrosurgical operation. The results indicated a significant increase of the contact angle on the nanostructured DLC-Cu thin films, and the antiadhesion properties were also observed in an animal model. Furthermore, the surgical temperature in the DLC-Cu electrosurgical unit was found to be significantly lower than the untreated unit when analyzed using 3D models and thermal images. In addition, DLC-Cu electrodes caused a relatively small injury area and lateral thermal effect. The results indicated that the nanostructured DLC-Cu thin film coating reduced excessive thermal injury and tissue adherence effect in the liver.

Effects of different radio-opacifying agents on physicochemical and biological properties of a novel root-end filling material

“…The contact angles of water and glycerol were measured by using a static sessile drop method under ambient conditions with an automatic goniometer CAM 200 (KSV Inc., Helsinki, Finland). A drop of deionized water or glycerol (3 μL) was placed on the disc shaped specimen (10 mm in diameter and 1 mm in thickness) surface and its profile was recorded immediately [ 24 ]. The contact angle was obtained and the mean of 5 measurements was determined for each group ( n = 5).…”

Physico-Chemical Approaches to Improve the Characteristics of Electrosurgical Instruments

“…Объединение достоинств покрытий на основе металлов и полимеров привело в разработке композиционных покрытий, обладающих лучшими характеристиками по сравнению с индивидуальными компонентами покрытия. Опубликован целый ряд работ, посвящённых композиционным покрытиям на основе алмазоподобного углерода, допированного наночастицами меди (DLC-Cu) [32][33][34][35]. Полученные покрытия значительно превосходят нержавеющую сталь по микротвердости (2250 Hv против 500 Hv), краевому углу смачивания (97,25±1,87° против 75,47±2,55°) и, что немаловажно, рабочая температура электрода с композиционным покрытием в среднем на 12% ниже, чем температура электрода без покрытия, что оказывает влияние на степень повреждения тканей.…”

Adhesion Behavior of Textured Electrosurgical Electrode in an Electric Cutting Process

“…The plasma was produced in a generator under the action of an electric field, but the process was unstable at a high power, making the whole machining process difficult to adjust and control. Shen et al [11] proposed the RF magnetron-sputtering technique for preparing DLC-Cu (diamond-like carbon) thin films on the electrode surface to reduce tissue adhesion. Surface coatings can reduce the thermal damage and tissue adhesion effectively, but these coatings were usually unstable and easily damaged at a high temperature.…”