As a pillar industry in the tertiary industry, the efficiency of its input and output is crucial to social and economic development. This paper takes Anhui tourism industry as the object of model validation, selects the number of star-rated hotels, the number of travel agencies and the number of tourism employees as input indicators, and the domestic tourism revenue and international tourism foreign exchange revenue of Anhui Province as output indicators, and analyzes the evaluation results of tourism input-output efficiency of Anhui Province from 2005 to 2017 using DEA model. The results of the study show that the technical efficiency and scale efficiency of Anhui tourism industry both show a wave-like rise, and should continue to optimize the allocation of resources and give full play to the advantages of tourism.