At present, aeroponic control is mainly regulated according to the environmental factors of aeroponics, such as the temperature, humidity, light intensity, carbon dioxide concentration, pH, and electrical conductivity (EC) of the nutrient solution. There is a lack of knowledge available in the literature for an aeroponic control system for plant growth information as the primary feedback signal. Therefore, a fuzzy logic-controlled aeroponics system was developed for the growth of lettuce as a feedback signal. After designing, the effectiveness test of system was performed with experiment having three treatments T1 (180C), T2 (220C) and without control (CK). The results show an increasing trend in shoot length, root length, and shoot area over time in all treatments. In terms of shoot area, the maximum of 345 cm² was observed in the T1 treatment, while the CK treatment had a minimum of 241.8 cm². Statistical analysis indicated that the T1 and T2 treatments were not significantly different, but both were significantly different from the CK treatment. The study demonstrates the effectiveness of the fuzzy logic control system and an 18°C nutrient solution temperature, resulting in improved lettuce growth and reduced root-to-shoot ratio. The findings suggest the potential of using fuzzy logic control in aeroponics for optimized cultivation outcomes.