Research on the Amount of Stimulus Differences According to Pharmacopuncture Injected dose and Characters Method^※

Abstract

Objectives : This study was designed to discover the difference in stimulation effect when the volume and insertion method of mountain ginseng pharmacopuncture was varied. Methods : 48 healthy people were randomly injected with 0.1, 0.3, 0.5, and 0.7 cc of mountain ginseng pharmacopuncture, perpendicularly or transversely at acupoints LI 9 and LI 10 . The subjects noted their level of stimulation on a 100 mm visual analog scale(VAS) immediately after, 3 minutes after, and 5 minutes after the treatment. Results : There was no significant statistical difference in the stimulation strength between perpendicular injection and transverse injection pharmacopuncture. There was significant statistical difference in the stimulation strength when the volume of pharmacopuncture was varied. As the volume of pharmacopuncture increased from 0.1 cc to 0.3 cc, and to 0.5 cc, the stimulation strength increased as well. Conclusions : We found that volume of pharmacopuncture may be a controlling element for mountain ginseng pharmacopuncture. Additional study is needed for pharmacopuncture's stimulation adjusting factors.

Panax ginseng Pharmacopuncture: Current Status of the Research and Future Challenges

“…Wild ginseng pharmacopuncture injected at acupoints (ST36 and ST37) did not significantly change the acupuncture sensations as compared with other types of complex-herb pharmacopuncture (e.g., BUM pharmacopuncture made of Calculus Bovis, Fel Ursi, Moschus) and saline injection [20]. Another study showed that only the volume of injected solution, but not the stimulation methods (perpendicular versus transverse injection) at acupoints, affected the subjective intensity reporting of pharmacopuncture stimulation [21].…”

“…Among the case reports, 18 used wild ginseng pharmacopuncture in patients with cancer [lung cancer (n = 17, patients); hepatocellular carcinoma, prostate cancer, colorectal cancer, or pancreatic cancer (n = 2, respectively); cervical cancer, thymus cancer, breast cancer, Signet ring cell carcinoma, bronchioloalveolar carcinoma, or tubulovillous adenoma (n = 1, respectively)] [34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51]. One hundred patients with rhinitis [56], 23 with skin wrinkles [21], three with amyotrophic lateral sclerosis (ALS) [53], and one with Behçet's disease, hepatitis, hepatocirrhosis [52], cervical dysplasia [54], neurofibroma [14], and acute demyelinating encephalomyelitis [55] were included in the systematic review. A RCT included 102 patients with depression and compared the effect and AEs of combined therapy composed of ginseng polysaccharides pharmacopuncture, Bupleurum pharmacopuncture, and paroxetine with those of paroxetine-only treatment [16].…”

“…Four studies [21,39,48,56] applied ginseng pharmacopuncture alone, and the others used various co-interventions such as antidepressants, anticancer drugs, analgesics, herbal medication, chemotherapy, cupping, moxibustion, acupuncture, diuretics, rehabilitation, surgery, and pharmacopuncture using other herbs. Fifteen studies involved pharmacopuncture performed intravenously, 10 involved injections in acupoints (three studies used both intravenous and acupoint injections [34,37,40]), and one involved injection into the sphenopalatine ganglion [56] (Figure 3).…”

Pharmacoacupuncture for the Treatment of Frozen Shoulder: protocol for a systematic review and meta-analysis

“…Both PA and CSI are injected into the affected lesion to exert anti-inflammatory effects [ 15 , 20 ]. PA and HD also have volume effects, with the injected material distending the surrounding tissue [ 3 , 21 ]. However, CSI and HD are injected into intra-articular lesions, presenting an infection risk, and possibly negatively impacting the surrounding rotator cuff tissue [ 3 , 22 , 23 ].…”

To evaluate the efficacy and safety of PLC in perimenopausal or postmenopausal women with Hot Flashes: study protocol for a randomized controlled trial

“…Pharmacopuncture is a combination of acupuncture and medication, and is a new therapy in which a purified herbal medicine is injected at an acupoint. It is widely used in China and Korea, and is also known as acupoint injection, herbal acupuncture, aqua acupuncture, and aquapuncture [16]. With its increasing use, various studies on pharmacopuncture have been initiated and are ongoing.…”