The components of Slovakia’s integrated transport infrastructure should be designed, constructed, maintained, and decommissioned at a reasonable cost and quality, respecting the relevant requirements of users, residents in the surrounding area, and the principles of sustainable development throughout its entire life cycle. A comprehensive integrated transport infrastructure must ensure multimodal, interoperable, and safe transport with the lowest possible carbon footprint, focused on regional development and cohesion, with maximum economically feasible minimization of environmental noise induced by traffic. This article provides the basis for fulfilling this premise in environmental noise reduction along the section of the first-class road I/59 from the village of Oravský Podzámok to the village of Likavka, where the current noise levels exceed the permissible values set by legislation. The solution to this problem is expected to be the construction of the R3 expressway, which is being considered in two variants.