This research paper delves into the subject of innovation and entrepreneurship in the field of medical education in China. It reviews relevant literature on education reform on medical innovation and entrepreneurship and identifies the challenges that higher medical education in China needs to address. These challenges include the integration of interdisciplinary knowledge, the need for in-depth integration of professional education with innovation and entrepreneurship education, the sustainable development of innovation and entrepreneurship education, and the lack of an innovation and entrepreneurship education management system. Additionally, the paper explores the current state of innovation and entrepreneurship education in the United States and highlights the importance of a teaching goal in medical innovation and entrepreneurship education. The study suggests that the United States' approach emphasizes participation rather than the result, which China can learn from. Furthermore, the paper analyzes three aspects: the lack of a system, the insufficient combination of professional education with innovation and entrepreneurship education, and the teaching management concept. The study proposes countermeasures to improve the construction of innovation and entrepreneurship integration systems, deepen the reform of medical courses, and innovate medical management mechanisms. The proposed strategies aim to provide references for the innovation and entrepreneurship education in Chinese medical colleges and universities based on the new medical science. Ultimately, this study provides valuable insights and recommendations for promoting innovation and entrepreneurship education in Chinese medical education.