2024
DOI: 10.1002/tox.24219
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Research on the toxicological prognostic significance of age‐related genes in endometrial cancer unveiling key factors in patient prognosis

Yongchao Yin,
Qian Niu,
Zhiqiang Wei
et al.

Abstract: This study investigates the influence of aging‐related genes on endometrial cancer, a prominent gynecological malignancy with rising incidence and mortality. By analyzing gene expression differences between cancerous and normal endometrial tissues, 42 aging‐related genes were identified as differentially expressed. Utilizing the TCGA‐UCEC sample, consensus clustering divided the samples into two molecular subgroups, Aging low and Aging high, based on their expression profiles. These subgroups showed distinct p… Show more

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