Packaging is an important economic component of the wine industry. However, while glass bottles are the leading wine container globally, their production and handling entail severe problems in increased carbon footprint impact and waste and logistic management. As a result, the wine packaging industry has developed and commercialised several alternatives to glass bottles, including aluminium cans. However, despite producers’ efforts in proposing alternative wine packaging, there are several barriers to their diffusion, especially in countries with a long tradition of wine consumption such as Italy, and it is still uncertain if and to what degree consumers would appreciate a wine in an aluminium can. This research investigates Italian wine consumers’ preferences and willingness to pay for canned wine through a survey and the contingent valuation method. We collected data from 551 consumers regarding attitudes and preferences about their wine consumption, alternative packaging acceptance, and motivations for accepting and refusing to buy it. Only a minority of the respondents declared they would buy canned wine, while the majority would refuse for reasons related to low-quality perception and poor consideration of alternative wine packaging. The lack of knowledge is one of the main obstacles to the diffusion of canned wine. However, canned wines could address different groups of wine drinkers and consumption occasions, increasing the opportunities for winemakers, especially among non-regular consumers.