Due to its flexibility, cable support glass curtain wall is sensitive to wind loads and its wind-induced dynamic response has attracted more and more attention recently. However, the wind-resistant study for this kind of structure mainly focuses on single-layer plane cable support curtain walls but is rare on irregular ones. In this paper, the wind-induced response of an L-shaped cable support glass curtain wall is analyzed. In order to truly reflect the force transmission, a finite element model of curtain wall is established to ensure collaborative deformation between glass and cable, including glass panel, cable, sealant, and claw connection. Timedomain vibration analysis of the curtain wall is carried out with the random sequence of multinode fluctuating wind velocity time history simulated by autoregressive linear filtering method based on Kaimal wind velocity spectrum. Four wind flow directions are specified, namely, 0 ∘ , 15 ∘ , 30 ∘ , and 45 ∘ , to analyze the wind-induced dynamic response of this structure with consideration of the fluid-structure interaction effect. Finally, the deflection of the glass surface is studied by statistical analysis of displacement so as to obtain the wind vibration coefficient suitable for structural design of practical projects, and the variation of cable force is investigated as well.