Research Progress in Fluorescent Probes for Arsenic Species

Abstract

Arsenic is a toxic non-metallic element that is widely found in nature. In addition, arsenic and arsenic compounds are included in the list of Group I carcinogens and toxic water pollutants. Therefore, rapid and efficient methods for detecting arsenic are necessary. In the past decade, a variety of small molecule fluorescent probes have been developed, which has been widely recognized for their rapidness, efficiency, convenience and sensitivity. With the development of new nanomaterials (AuNPs, CDs and QDs), organic molecules and biomolecules, the conventional detection of arsenic species based on fluorescence spectroscopy is gradually transforming from the laboratory to the portable kit. Therefore, in view of the current research status, this review introduces the research progress of both traditional and newly developed fluorescence spectrometry based on novel materials for arsenic detection, and discusses the potential of this technology in the rapid screening and field testing of water samples contaminated with arsenic. The review also discusses the problems that still exist in this field, as well as the expectations.

Biotechnology Advances in Bioremediation of Arsenic: A Review

“…Organic forms of As are less toxic in nature than inorganic As forms. In general, inorganic As exists in four different oxidation states: As 3- (arsine), As 0 (elemental arsenic), As 3+ (arsenite) and As 5+ (arsenate) ( Figure 2 ) [ 1 , 10 , 15 , 16 ]. Of these, arsenate (HAsO 4 2- , H 2 AsO 4 − ) and arsenite (As(OH) 3 , HAsO 3 ) are most abundant in soils and waters under oxic and anoxic conditions [ 1 , 10 , 15 ].…”

“…As contamination of water is mainly caused by the dissolution of rocks, minerals or ores, and by industrial effluents, including mining waste. In the soluble form, As(V) is usually present in oxygenated water such as wells, while As(III) is found in reducing conditions such as groundwater or deep lake sediments [ 1 , 10 , 11 ]. Both inorganic forms of As have been found in soils as well, and can be transported in the food chain by plant uptake and food crop consumption, inducing different toxic effects [ 12 ].…”

Construction of a novel cuboid-shape Mn-Urea nanozyme with arsenic(v)-enhanced oxidase-like activity as a colorimetric probe for the selective detection of inorganic arsenic

“…[6][7][8] However, these instrument-based methods for As detection require rigorous lab environment, expensive instruments and professional operation, 9,10 which are unable to meet the requirements of convenient and quick testing. To address these issues, nanozyme-based optical analytical methods with easy operation and high sensitivity, such as colorimetry 5,11 and fluorometry, 12,13 are employed in the detection of inorganic As. Furthermore, colorimetry can rapidly and intuitively display the concentration of the target analyte via chromogenic reactions, which show remarkable advantages in practical applications.…”

Detection of Arsenic(V) by Fluorescence Sensing Based on Chlorin e6-Copper Ion

“…The toxicity of inorganic arsenic is much greater than that of organic arsenic, and As(III) is recognized as the most toxic of the inorganic arsenic forms [ 3 ]. As(III) can bind to enzymes or proteins containing sulfhydryl (–SH) functional groups in the body, altering their conformation and function and affecting normal physiological processes in the body [ 4 , 5 ]. As(III) and As(V) are structurally similar to phosphite and phosphate ions, which can permanently substitute the phosphate groups to interrupt the transformation of ATP to ADP [ 5 ].…”