2024
DOI: 10.1002/ddr.70027
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Research Progress of Endoplasmic Reticulum Targeting Metal Complexes in Cancer Therapy

Shihang Xu,
Xiaoling Wu,
Jia Zhu
et al.

Abstract: The development of anticancer drugs that target different organelles has received extensive attention due to the characteristics of cancer recurrence, metastasis, and drug resistance. The endoplasmic reticulum (ER) is an important structure within the cell that is primarily responsible for protein synthesis, folding, modification, and transport and plays a crucial role in cell function and health. ER stress activation induces cancer cell apoptosis. New anticancer drugs with different anticancer mechanisms and … Show more

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