Research progress of the engagement of inorganic nanomaterials in cancer immunotherapy

Peng, Tingwei; Xu, Tianzhao; Liu, Xinghui

doi:10.1080/10717544.2022.2086940

Cited by 11 publications

(5 citation statements)

References 92 publications

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“…Inorganic nanomaterials are the easiest to manufacture and can be classified as metals, semiconductors, and nonmetals such as gold, silver, silicon dioxide, titanium dioxide, rare earth oxides, iron oxide, zinc oxide, and quantum dots [54]. These have received widespread attention in biomedicine due to their unique size and properties, including their optical, electrical, and magnetic characteristics [55].…”

Section: Inorganic Materials Nanoparticle Delivery Systemmentioning

confidence: 99%

Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry

Guo,

Awais,

Fei

et al. 2024

Animals

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Silk fibroin (SF), a unique natural polymeric fibrous protein extracted from Bombyx mori cocoons, accounts for approximately 75% of the total mass of silk. It has great application prospects due to its outstanding biocompatibility, biodegradability, low immunogenicity, and mechanical stability. Additionally, it is non-toxic and environmentally friendly. Nanoparticle delivery systems constructed with SF can improve the bioavailability of the carriers, increase the loading rates, control the release behavior of the deliverables, and enhance their action efficiencies. Animal husbandry is an integral part of agriculture and plays a vital role in the development of the rural economy. However, the pillar industry experiences a lot of difficulties, like drug abuse while treating major animal diseases, and serious environmental pollution, restricting sustainable development. Interestingly, the limited use cases of silk fibroin nanoparticle (SF NP) delivery systems in animal husbandry, such as veterinary vaccines and feed additives, have shown great promise. This paper first reviews the SF NP delivery system with regard to its advantages, disadvantages, and applications. Moreover, we describe the application status and developmental prospects of SF NP delivery systems to provide theoretical references for further development in livestock production and promote the high-quality and healthy development of animal husbandry.

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Section: Inorganic Materials Nanoparticle Delivery Systemmentioning

confidence: 99%

Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry

Guo,

Awais,

Fei

et al. 2024

Animals

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“…MSNs have great potential for use in the treatment of various diseases such as cancer, diabetes, and Alzheimer's disease. 44,45…”

Section: Mesoporous Silica Nanocompositementioning

confidence: 99%

Recent advances in glucose-oxidase-based nanocomposites for diabetes diagnosis and treatment

Yang

Cai

et al. 2023

J. Mater. Chem. B

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“…Additionally, various immune checkpoints are modulated with different formulations of inorganic NPs. Comprehensive research studies have shown that aluminum oxide NPs can upregulate the expressions of CD80, CD86, MHC-1, and MHC-2 molecules in dendritic immune cells [127]. The overexpression of these checkpoint molecules stimulates the secretion of interferon-γ to inhibit tumorigenic growth.…”

Section: Modern Radiotherapymentioning

confidence: 99%

Inorganic Nanoparticles as Radiosensitizers for Cancer Treatment

Babu,

Stoltz,

Mittal

et al. 2023

Nanomaterials

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Nanotechnology has expanded what can be achieved in our approach to cancer treatment. The ability to produce and engineer functional nanoparticle formulations to elicit higher incidences of tumor cell radiolysis has resulted in substantial improvements in cancer cell eradication while also permitting multi-modal biomedical functionalities. These radiosensitive nanomaterials utilize material characteristics, such as radio-blocking/absorbing high-Z atomic number elements, to mediate localized effects from therapeutic irradiation. These materials thereby allow subsequent scattered or emitted radiation to produce direct (e.g., damage to genetic materials) or indirect (e.g., protein oxidation, reactive oxygen species formation) damage to tumor cells. Using nanomaterials that activate under certain physiologic conditions, such as the tumor microenvironment, can selectively target tumor cells. These characteristics, combined with biological interactions that can target the tumor environment, allow for localized radio-sensitization while mitigating damage to healthy cells. This review explores the various nanomaterial formulations utilized in cancer radiosensitivity research. Emphasis on inorganic nanomaterials showcases the specific material characteristics that enable higher incidences of radiation while ensuring localized cancer targeting based on tumor microenvironment activation. The aim of this review is to guide future research in cancer radiosensitization using nanomaterial formulations and to detail common approaches to its treatment, as well as their relations to commonly implemented radiotherapy techniques.

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Research progress of the engagement of inorganic nanomaterials in cancer immunotherapy

Cited by 11 publications

References 92 publications

Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry

Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry

Recent advances in glucose-oxidase-based nanocomposites for diabetes diagnosis and treatment

Inorganic Nanoparticles as Radiosensitizers for Cancer Treatment

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