With the continuous progress and innovation of science and technology, the demand and requirements for energy in modern society are getting higher and higher. The system application of liquid cooling and intelligent control algorithm coupling energy management can adapt to this demand and provide more efficient, accurate and intelligent energy management solutions. On the basis of a brief introduction to the current energy problems, the principle of liquid cooling technology and intelligent control algorithm are expounded, the design and key technologies of liquid cooling system and intelligent control algorithm are analyzed. The liquid cooling system based on fuzzy control is studied. The liquid cooling system based on fuzzy control can quickly and accurately respond to equipment temperature changes, avoid equipment damage due to overheating, and improve energy utilization efficiency and reduce energy waste. On the basis of a brief introduction to the current energy problems, this study describes the principle of liquid cooling technology and intelligent control algorithm, focuses on the design and key technologies of liquid cooling system and intelligent control algorithm, and studies the liquid cooling system based on fuzzy control. The liquid cooling system based on fuzzy control can quickly and accurately respond to equipment temperature changes, avoid equipment damage due to overheating, and can improve energy utilization efficiency and reduce energy waste.