Research progress on inosine monophosphate deposition mechanism in chicken muscle

Huang, Zengwen; Zhang, Juan; Gu, Ye; Cai, Zhen; Feng, Xiaoran; Yang, Chaoyun; Xin, Guosheng

doi:10.1080/10408398.2020.1833832

Cited by 23 publications

(21 citation statements)

References 79 publications

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“…IMP can be converted to adenosine diphosphate or guanosine-5′-diphosphate and then to adenosine triphosphate or guanosine trisphosphate ( 39 ). IMP is an important indicator of meat quality and freshness in animals ( 40 , 41 ). However, the role of IMP in humans is rarely mentioned.…”

Section: Discussionmentioning

confidence: 99%

Differential metabolites in cirrhotic patients with hepatitis B and muscle mass loss

Liu

Han²,

Bi³

et al. 2023

Front. Nutr.

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BackgroundSarcopenia leads to complications (infections, hepatic encephalopathy and ascites) and poor overall survival in patients with cirrhosis, in which the phenotypic presentation is loss of muscle mass. This study aimed to reveal the metabolic profile and identify potential biomarkers in cirrhotic patients with hepatitis B virus and muscle mass loss.MethodTwenty decompensated cirrhotic patients with HBV and muscle mass loss were designated Group S; 20 decompensated cirrhotic patients with HBV and normal muscle mass were designated Group NS; and 20 healthy people were designated Group H. Muscle mass loss was defined as the skeletal muscle mass index less than 46.96 cm2/m2 for males and less than 32.46 cm2/m2 for females. Gas chromatography–mass spectrometry was used to explore the distinct metabolites and pathways in the three groups.ResultsThirty-seven metabolic products and 25 associated metabolic pathways were significantly different in the Group S patients from Group NS patients. Strong predictive value of 11 metabolites (inosine-5′-monophosphate, phosphoglycolic acid, D-fructose-6-phosphate, N-acetylglutamate, pyrophosphate, trehalose-6-phosphate, fumaric acid, citrulline, creatinine, (r)-3-hydroxybutyric acid, and 2-ketobutyric acid) were selected as potential biomarkers in Group S patients compared with Group NS patients. Two pathways may be associated with loss of muscle mass in patients with liver cirrhosis: amino acid metabolism and central carbon metabolism in cancer.ConclusionSeventy differential metabolites were identified in patients who have liver cirrhosis and loss of muscle mass compared with patients who have cirrhosis and normal muscle mass. Certain biomarkers might distinguish between muscle mass loss and normal muscle mass in HBV-related cirrhosis patients.

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Section: Discussionmentioning

confidence: 99%

Differential metabolites in cirrhotic patients with hepatitis B and muscle mass loss

Liu

Han²,

Bi³

et al. 2023

Front. Nutr.

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“…This result showed that the CF content of breast meat in white light group was lower than that in other light groups. IMP is a flavor-enhancing substance, which plays a critical role in the umami taste of the muscle, making the content of IMP an important umami taste indicator [ 28 ]. At present, the research on the effect of muscle IMP content focuses on genetic factors, feeding methods, nutritional factors and the age at slaughter, and there is no research report on the influence of light environment test on it, although the muscle adenosine triphosphate (ATP) content was measured in this test, the content was not detected, which may be due to the rapid decomposition of ATP.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of light-emitting diode colors and intensities on slaughter performance, meat quality and serum antioxidant capacity in caged broilers

Tan¹,

Zhou²,

Shi³

et al. 2023

Anim Biosci

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This study was to evaluate the interaction of three different light-emitting diode (LED) light colors (white, green, and blue) and three intensities (5, 10, and 15 lx) on slaughter performance, meat quality and serum antioxidant capacity of broilers raised in three-layer cages. MethodsA total of 648 8-days-old male broiler chicks (Cobb-500) were randomly assigned in 3×3 factorially arranged treatments: three light colors (specifically, white, blue, and green) and three light intensities (namely, 5, 10, and 15 lx) for 35 days. Each treatment consisted of 6 replicates of 12 chicks. The test lasted for 35 days. ResultsThe semi-eviscerated weight percentage (SEWP) in 5 lx white was higher than that in 15 lx (P<0.01). The eviscerated weight percentage (EWP) (P<0.05) and water-loss percentage (WLP) (P<0.01) decreased in 10 lx white light than those in green light. Under blue light, the content of hypoxanthine (Hx) in muscle was lower than that under white and green light (P<0.01). The content of malondialdehyde (MDA) in 15 lx blue light was higher than that in 10 lx green light (P<0.05). Light color had an extremely significant effect on TMP, WLP, Hx and crude protein (CP) content (P<0.01). Light intensity had a significant effect on SEWP, EWP, Lightness (L*) value (P<0.05), WLP (P<0.01), and the contents of superoxide dismutase (SOD) (P<0.05), MDA (P<0.01), glutathione peroxidase (GSH-Px) (P<0.01). The interaction effects of light color and intensity had a significant effect on inosine (HxR) content (P<0.01). ConclusionUsing white LED light with 10 lx light intensity can significantly improve the chicken quality of caged Cobb broilers, improve the content of inosine acid in chicken breast and enhance the A c c e p t e d A r t i c l e antioxidant capacity of the body. We suggest that the broiler farm can use 10 lx white LED light source for lighting in 8-42 days.

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“…In addition, its degradation products combined with certain amino acids can result in a Mailard reaction under heating conditions to produce volatile substances, which can affect meat freshness and are a key factor in determining the umami of meat. Related studies [ 6 , 69 ] have reported that the ADSL gene is one of the main enzymes for IMP deposition in animal organisms and plays an important role in IMP synthesis, which is closely related to meat quality [ 8 , 70 ]. A high expression of the ADSL gene and the GARS-AIRS-GART gene combination enhances the IMP content in chicken meat [ 71 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Mulberry Leaf TMR on Growth Performance, Meat Quality and Expression of Meat Quality Master Genes (ADSL, H-FABP) in Crossbred Black Goats

Long

Han

Zhao

et al. 2022

Foods

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This study was conducted to examine the effect of a mulberry leaf total mixed ration (TMR) diet on growth performance, apparent digestibility, meat quality and the expression of related meat-quality genes (ADSL, H-FABP) in crossbred black goats. Forty-four Guizhou crossbred black goats (Nubian black goat ♂ × Guizhou black goat ♀), weighing 33.43 ± 0.55 kg, were chosen. The goats were randomly divided into four groups, with 11 test replicates in each group. Group I was the control group and fed with the traditional feeding method of roughage and concentrate supplement without adding mulberry leaf. Group II was fed with a 40% mulberry leaf pellet TMR diet. Group III was fed with a freshly processed 40% mulberry leaf TMR diet. Group IV was fed with a 40% mulberry leaf fermented total mixed rations (FTMR) diet. The results showed that the average daily gain (ADG) of group II was significantly higher than that of group I and III (p < 0.05). The apparent digestibility of group II of ether extract (EE) and neutral detergent fiber (NDF) was significantly higher than that of group I (p < 0.05), and the apparent digestibility of dry matter (DM) and crude protein (CP) was significantly higher than that of group I (p < 0.01). Compared with group I, meat in group II had lower meat color lightness (L*) and yellowness (b*) values (p < 0.01) in the Longissimus thoracis et lumborum. The shear force of group II was significantly lower than that of group I (p < 0.05). The total fatty acids (TFA) of group II was significantly higher than that of groups I and III (p < 0.05), but the total saturated fatty acids (SFA) of group II was significantly lower that than of group I (p < 0.01). Subsequently, the Unsaturated fatty acids (USFA), Monounsaturated fatty acids (MUFA), and Polyunsaturated fatty acids (PUFA) of group II were significantly higher than those in group I (p < 0.01). The contents of total amino acids (TAA), total essential amino acids (EAA), total non-essential amino acids (NEAA) and total of major fresh-tasting amino acids (DAA) of groups II, III and IV were significantly higher than those of group I (p < 0.05), as well as the contents of IMP (p < 0.01). The expression of the H-FABP gene in the arm triceps of group II was significantly higher than that of groups I, III and IV (p < 0.05). The expression of the ADSL gene in the Longissimus thoracis et lumborum and biceps femoris of group II was significantly higher than that of group I (p < 0.05). Collectively, the results of the current study indicated that the mulberry leaf TMR diet improved the growth performance, apparent digestibility and expression of related meat-quality master genes (ADSL, H-FABP) in crossbred black goats, which promoted the deposition of intramuscular fat (IMF) and inosinic acid (IMP) and improved the composition of fatty acids and amino acids in the muscles.

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Research progress on inosine monophosphate deposition mechanism in chicken muscle

Cited by 23 publications

References 79 publications

Differential metabolites in cirrhotic patients with hepatitis B and muscle mass loss

Differential metabolites in cirrhotic patients with hepatitis B and muscle mass loss

Evaluation of light-emitting diode colors and intensities on slaughter performance, meat quality and serum antioxidant capacity in caged broilers

Effect of Mulberry Leaf TMR on Growth Performance, Meat Quality and Expression of Meat Quality Master Genes (ADSL, H-FABP) in Crossbred Black Goats

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