Research progress on the influence of traditional Chinese medicine on tumor microenvironment therapy

Abstract

More and more attention has been paid to the tumor microenvironment. The occurrence, development, metastasis, and drug resistance of tumor are closely related to the tumor microenvironment. At the same time, the application of traditional Chinese medicine (TCM) in tumor prevention and treatment has attracted more and more attention due to its regulatory effect on tumor cells and tumor microenvironment. The holistic view and multitarget regulatory view of TCM make it very suitable for the regulation of tumor microenvironment. This article will review the current research status of the molecular mechanism of TCM regulation of tumor microenvironment from three aspects: TCM can reverse the inhibitory phenotype of immune cells, TCM can enhance the immune response to tumor cells, and TCM clinical application.