Research Review of Human Infections with Avian Influenza A(H7N9) Virus in China

Abstract

Abstract. The emergence of H7N9 virus attracted worldwide concerns about the possibility of a new influenza pandemic in March 2013, and the human cases were mainly distributed in the southeast coastal areas in China, and the winter-spring season was the peak period for human infection with H7N9 virus. The studies on Human infections with avian influenza A(H7N9) virus at present are mainly divided into three categories: gene research, animal model research, outbreak simulation and risk prediction model research. The former two kinds of studies can provide lots of useful information on the mechanisms of H7N9 virus and the principles of infection, and the third kind of research can provide scientific basis and information decision-making tool for the prevention and monitoring of Human infections with avian influenza A(H7N9) virus. The impacts of environmental factors on H7N9 outbreak should be taken into account in the future study, and the closure of live poultry market as well as the suspension of live poultry trading should be vigorously pursued to control the spread of H7N9 epidemic in the high incidence areas in China.