Research Status and Hotspots of Chronic Osteomyelitis: A Bibliometric and Visualized Analysis

Abstract

Objective The treatment of chronic osteomyelitis (COM) is extremely challenging for physicians and patients. It is of great significance to explore the research status, development trend and future research hotspots in the field of COM to promote the development of this field. This study is aimed to explore the global research status of COM and predict its future research hotspots based on bibliometric and visualized analysis. Methods Web of Science core collection database was used to search the related literature of COM from 1994 to 2020. All data were imported into Microsoft Excel 2019 for collation. Additionally, the literature quality of countries, authors, journals, and institutions is evaluated. The VOS viewer software was used for conducting co‐analysis, co‐citation analysis, and keyword co‐occurrence analysis of literature to analyze the global status and predict the future hotspots of the COM field. Results A total of 726 articles were retrieved in this study. The number of global publications shows a trend of wave growth, but the increase is not significant. It is expected that the number of COM articles will remain at more than 50 per year in the next decade. The COM literature published in the United States (Publications = 160, H index = 37, average citations per item = 28.63) is of the highest quality. Girschick HJ (Publications = 16, H index = 14, average citations per item = 52.25) is the most contributed scholar in the field of COM. UNIV IOWA (Publications = 15, H index = 11, average citations per item = 57.27) and UNIV WURZBURG (Publications = 18, H index = 15, average citations per item = 47.5) are influential institutions in the field of COM. The results of co‐occurrence analysis show that the field of COM can be roughly divided into the following five modules: COM surgical research, COM basic research, COM diagnosis‐related research, chronic recurrent multifocal osteomyelitis (CRMO)‐related research, risk factors of COM. Risk factors of COM are the module with the highest concentration of hot words. Conclusion COM‐related research will continue to develop further in the next decade. The diagnosis research and risk factors of COM are the most popular research modules in recent years. Some controversial or troubled issues including the efficacy of perforator flap and fascia flap covering soft tissue, searching exclusive detection methods for the diagnosis of COM and bisphosphonates and biological agents in the treatment of CRMO may lead to the development of the COM field.

Outcome of Chronic Foot Osteomyelitis Treated With Hyperbaric Oxygen: An Observational Study

“…These outcomes are not merely statistical revelations; they signify a potential transformative approach in tackling chronic osteomyelitis, providing a novel perspective corroborated by existing literature. 12 The principal microorganisms identified were Staphylococcus aureus and Streptococcus spp. These findings are coherent with existing literature, demonstrating the persistent role of these microorganisms in the onset and progression of osteomyelitis.…”

“…These outcomes are not merely statistical revelations; they signify a potential transformative approach in tackling chronic osteomyelitis, providing a novel perspective corroborated by existing literature. 12…”

Rapid and effective treatment of chronic osteomyelitis by conductive network-like MoS2/CNTs through multiple reflection and scattering enhanced synergistic therapy

“…Chronic orthopedic infection is one of the major complications of orthopedic trauma and clinical surgery [ 1 ]. Chronic osteomyelitis (COM) is a chronic, persistent disease of the bone marrow, periosteum, bone cortex, and surrounding tissues caused by pathogenic bacteria or aseptic inflammation from host tissue necrosis, acute osteomyelitis following trauma, diabetic foot, implant surgery infection, or blood dissemination, and associated with bone destruction and dead bone formation [ [2] , [3] , [4] , [5] ]. It is difficult to treat, but if not treated appropriately and in a timely manner, it can lead to life-threatening conditions, such as joint dysfunction and physical disability [ 6 ].…”