This chapter positions itself between the demographic and epidemiological transitioning of the youngest world region in terms of population with its leapfrogging of ICT, specifically cell phone technology. Against the background of poverty and the continuing HIV and AIDS epidemic in (South) Africa, this contribution examines the deep penetration and agentic uptake of cell phones by older persons. It situates these users within their physical and family environments, and within the broader dynamics of intergenerational encounters with younger people. Whereas cell phones are often associated with youth culture, this chapter argues that older persons are very much part of the presence, circulation, and use of information and communication technologies (ICT), albeit for most of them on a basic level. Key cross-cutting strategic considerations for their ICT uptake involve intergenerational investment; harnessing the potential of new technologies for older persons; and inclusion of their input in ICT responses to their needs. To further the aim of achieving a society for all ages, ICT responses are proposed in the domains of social and health care, service delivery, and later-life learning.