Resection of pulmonary metastases in six patients with disease-free interval greater than 10 years

Kamiyoshihara, Mitsuhiro; Hirai, Toshikazu; Kawashima, Osamu; Morishita, Yasuo

doi:10.1016/s0003-4975(98)00347-6

Cited by 17 publications

(9 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These five-year survival rates range from 38% to 42%3,4) in pulmonary metastasis and 25% to 34%66) in hepatic metastasis. In our institute, similar results have been obtained7, 8), and surgical intervention is the first treatment of choice if patients can tolerate surgery. However, surgical treatment for multiorgan metastases from colorectal cancer is still controversial.…”

Section: Introductionsupporting

confidence: 76%

Resection of Pulmonary and Antecedent Hepatic Metastases Arising from Colon Cancer. Report of a Case.

Kamiyoshihara

Ohtani

Yoshida

et al. 2000

kmj

Self Cite

View full text Add to dashboard Cite

Although surgical resection is a suitable treatment for localized metastases from colorectal cancer, it remains controversial for multiorgan metastases. We present herein a case of a 59-year-old woman, who underwent resection of pulmonary and antecedent hepatic metastases arising from colon cancer. The patient's postoperative course was uneventful, and there has been no evidence of recurrence for 23 months after the first operation. We report this case and discuss the operative indication for multiorgan metastases arising from colorectal cancer.

show abstract

Section: Introductionsupporting

confidence: 76%

Resection of Pulmonary and Antecedent Hepatic Metastases Arising from Colon Cancer. Report of a Case.

Kamiyoshihara

Ohtani

Yoshida

et al. 2000

kmj

Self Cite

View full text Add to dashboard Cite

show abstract

“…Radiotherapy is the alternative treatment for patients with medically inoperable primary non-small-cell lung cancer (NSCLC) [1], and also for patients with slow growing metastatic lung tumors [2] which when managed with high dose localized radiotherapy can prolong patients' symptom-free status.…”

Section: Introductionmentioning

confidence: 99%

Hypofractionated radiotherapy for lung tumors with online cone beam CT guidance and active breathing control

et al. 2010

View full text Add to dashboard Cite

BackgroundTo study the set-up errors, PTV margin and toxicity of cone beam CT (CBCT) guided hypofractionated radiotherapy with active breathing control (ABC) for patients with non-small cell lung cancer (NSCLC) or metastatic tumors in lung.Methods32 tumors in 20 patients were treated. Based on the location of tumor, dose per fraction given to tumor was divided into three groups: 12 Gy, 8 Gy and 6 Gy. ABC is applied for every patient. During each treatment, patients receive CBCT scan for online set-up correction. The pre- and post-correction setup errors between fractions, the interfractional and intrafractional, set-up errors, PTV margin as well as toxicity are analyzed.ResultsThe pre-correction systematic and random errors in the left-right (LR), superior-inferior (SI), anterior-posterior (AP) directions were 3.7 mm and 5.3 mm, 3.1 mm and 2.1 mm, 3.7 mm and 2.8 mm, respectively, while the post-correction residual errors were 0.6 mm and 0.8 mm, 0.8 mm and 0.8 mm, 1.2 mm and 1.3 mm, respectively. There was an obvious intrafractional shift of tumor position. The pre-correction PTV margin was 9.5 mm in LR, 14.1 mm in SI and 8.2 mm in AP direction. After CBCT guided online correction, the PTV margin was markedly reduced in all three directions. The post-correction margins ranged 1.5 to 2.1 mm. The treatment was well tolerated by patients, of whom there were 4 (20%) grade1-2 acute pneumonitis, 3 (15%) grade1 acute esophagitis, 2 (10%) grade1 late pneumonitis and 1 (5%) grade 1 late esophagitis.ConclusionThe positioning errors for lung SBRT using ABC were significant. Online correction with CBCT image guidance should be applied to reduce setup errors and PTV margin, which may reduce radiotherapy toxicity of tissues when ABC was used.

show abstract

“…In addition, genetic factors and inflammatory bowel disease place certain persons at increased risk (30–33), although gene alterations have only been found in small percentages of patients with colon/rectum cancer (34). Pulmonary metastases of colon/rectum cancer occur not infrequently and may be detected even after long disease‐free periods (3, 35–39).…”

Section: Discussionmentioning

confidence: 99%

“…The extent of tumor vascularization has been reported to be an additional prognosis‐associated parameter in colon cancer patients (2, 36, 49), although this parameter is frequently not quantitatively determined. Within the panel of measured vascularization‐associated features of the primary tumors, the absolute value of the vascular circumference had the strongest association with the disease‐free interval, and the smallest vascular diameter measured in the metastases a high correlation with the total survival.…”

Section: Discussionmentioning

confidence: 99%

Primary colorectal carcinomas and their intrapulmonary metastases: Clinical, glyco‐, immuno‐ and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival

Kayser¹,

Zink²,

André

et al. 2002

APMIS

View full text Add to dashboard Cite

Despite intra- and interindividual variations, vascularization properties and features such as bcl-2 positivity and CEA- and galectin-3-associated structural entropy in primary tumors or metastases are described as independent prognostic features. Absence of lymph node involvement or limited tumor stages of colon/rectal carcinomas should not exclude patients from thorough postsurgical scrutiny to detect lung metastases.

show abstract

Resection of pulmonary metastases in six patients with disease-free interval greater than 10 years

Cited by 17 publications

References 8 publications

Resection of Pulmonary and Antecedent Hepatic Metastases Arising from Colon Cancer. Report of a Case.

Resection of Pulmonary and Antecedent Hepatic Metastases Arising from Colon Cancer. Report of a Case.

Hypofractionated radiotherapy for lung tumors with online cone beam CT guidance and active breathing control

Primary colorectal carcinomas and their intrapulmonary metastases: Clinical, glyco‐, immuno‐ and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival

Contact Info

Product

Resources

About