Residue degradation, transfer and risk assessment of pyriproxyfen and its metabolites from tea garden to cup by ultra performance liquid chromatography tandem mass spectrometry

Zhong, Qing; Wang, Min; Luo, Fengjian; Wang, Xinru; Zhou, Li; Zhang, Xinzhong

doi:10.1002/jsfa.11746

Cited by 8 publications

(5 citation statements)

References 30 publications

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“…The accuracy and precision of the method were estimated with recovery experiments for each matrix in five replicates at four spiked levels (0.005, 0.05, 1 and 10 mg L −1 for fresh tea shoots and dry tea, 0.0005, 0.005, 0.01, 0.1 mg L −1 for tea infusion). Referring to the intensity of the minimum concentration level in linear range, the signal-to-noise (S/N) of 3 was used for definition of the limit of detection (LODs) [18]. The limit of quantitation (LOQs) were defined as the minimum spiked level to meet the requirements of recovery and relative standard deviations (RSDs).…”

Section: Methods Validationmentioning

confidence: 99%

Establishment of a QuEChERS-UPLC-MS/MS Method for Simultaneously Detecting Tolfenpyrad and Its Metabolites in Tea

Wang

et al. 2022

Agronomy

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An analytical method simultaneously detecting pesticide and its metabolites, especially with higher toxicity, was urgently needed for supervision and safety evaluation of agricultural products. In the present study, a modified QuEChERS method coupled with a ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for simultaneous determination of tolfenpyrad (TFP) and its metabolites in tea matrices (fresh tea shoots, green tea, black tea, green tea infusion and black tea infusion) was established. The method validation showed good linearity (correlation coefficients ≥ 0.9945), accuracy (recoveries in 75.38–109.90%), sensitivity (limits of quantification ≤ 0.05 mg kg−1), and precision (relative standard deviations ≤ 19.09%). The established method was then applied to detect 40 market samples, resulting in 60.0% positive rate of TFP, besides, two metabolites including PT-CA, which is more toxic than the parent TFP, and PT-OH were also detected in the samples with high TFP residue(≥0.048 mg kg−1). The method established in the present work was thus of significant importance in comprehensive monitoring and of TFP in tea products.

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Section: Methods Validationmentioning

confidence: 99%

Establishment of a QuEChERS-UPLC-MS/MS Method for Simultaneously Detecting Tolfenpyrad and Its Metabolites in Tea

Wang

et al. 2022

Agronomy

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“…To ensure the scientific and safe application of difenoconazole, the risk quotients (RQ) method [31][32][33] was used to represent the long-term (chronic) dietary risk assessment. RQ was determined based on the national estimated daily intake (NEDI) and the acceptable daily intake (ADI), which were calculated in the following equation [34][35][36].…”

Section: Dietary Risk Assessmentmentioning

confidence: 99%

Dissipation, Residue Behavior and Dietary Risk Assessment of Difenoconazole on Jujube (Ziziphus jujuba Mill.)

Zhao

Liao

et al. 2022

Agronomy

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Difenoconazole is a triazole germicide that is usually applied to prevent fungal diseases on crops with high efficiency and safety. Jujube is a spiny Rhamnaceous plant that originated in China more than 4000 years ago and is extensively cultivated in northern China nowadays. To evaluate the safety of difenoconazole in jujube, supervised field trials were carried out in six provinces of China, and the final residue and dissipation behavior of difenoconazole on jujube were determined by gas chromatography (GC). The results showed that when addition levels were 0.02, 0.2, and 2 mg·kg−1, average recoveries of the aforementioned method for difenoconazole in jujube can be put into the range of 73–108%, and relative standard deviation (RSD) was 3–9%. The limit of quantitation (LOQ) for this method was 0.02 mg·kg−1. In the final residue test, difenoconazole was sprayed to deal with the jujube at 100 and 150 mg·kg−1 doses twice or three times, respectively, while the dissipation test was applied only once at a 150 mg·kg−1 dose. Final residue testing results have revealed that when jujube samples were harvested and tested at 7, 14, and 21 days post-application, difenoconazole residues in samples were 0.11–1.59, 0.05–0.77, 0.04–0.63 mg·kg−1, respectively. The dissipation testing results showed that the digestion process of difenoconazole in jujube tends to be a gradual reduction process and the dynamic regularity of the residue dissipation proves consistent with the first-order dynamics reaction equation. The half-life (t1/2) for difenoconazole residue dissipation in Qingdao and Yuncheng was 13.1 days and 16.5 days, respectively. The risk quotient (RQ) was 84.9% lower than 100%, showing that dietary intake risk to difenoconazole was acceptable and the maximum residue limit (MRL) of difenoconazole on jujube is recommended to be 2 mg·kg−1.

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“…The absence of quantitative indicators poses challenges to tea quality control for producers, consumers, and regulatory agencies. In recent years, various analytical techniques, including thin-layer chromatography [ 11 , 12 ], high-performance liquid chromatography [ 13 , 14 ], and ultra-performance liquid chromatography-tandem mass spectrometry [ 15 , 16 ], have been utilized to determine the chemical composition of tea. However, most of these studies have focused on only a few chemical markers from a small number of teas.…”

Section: Introductionmentioning

confidence: 99%

Quantitative Analysis of Bioactive Compounds in Commercial Teas: Profiling Catechin Alkaloids, Phenolic Acids, and Flavonols Using Targeted Statistical Approaches

Chen,

Lai,

You

et al. 2023

Foods

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Tea, an extensively consumed and globally popular beverage, has diverse chemical compositions that ascertain its quality and categorization. In this investigation, we formulated an analytical and quantification approach employing reversed-phase ultra-high-performance liquid chromatography (UHPLC) methodology coupled with diode-array detection (DAD) to precisely quantify 20 principal constituents within 121 tea samples spanning 6 distinct variants. The constituents include alkaloids, catechins, flavonols, and phenolic acids. Our findings delineate that the variances in chemical constitution across dissimilar tea types predominantly hinge upon the intricacies of their processing protocols. Notably, green and yellow teas evinced elevated concentrations of total chemical moieties vis à vis other tea classifications. Remarkably divergent levels of alkaloids, catechins, flavonols, and phenolic acids were ascertained among the disparate tea classifications. By leveraging random forest analysis, we ascertained gallocatechin, epigallocatechin gallate, and epicatechin gallate as pivotal biomarkers for effective tea classification within the principal cadre of tea catechins. Our outcomes distinctly underscore substantial dissimilarities in the specific compounds inherent to varying tea categories, as ascertained via the devised and duly validated approach. The implications of this compositional elucidation serve as a pertinent benchmark for the comprehensive assessment and classification of tea specimens.

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Residue degradation, transfer and risk assessment of pyriproxyfen and its metabolites from tea garden to cup by ultra performance liquid chromatography tandem mass spectrometry

Cited by 8 publications

References 30 publications

Establishment of a QuEChERS-UPLC-MS/MS Method for Simultaneously Detecting Tolfenpyrad and Its Metabolites in Tea

Establishment of a QuEChERS-UPLC-MS/MS Method for Simultaneously Detecting Tolfenpyrad and Its Metabolites in Tea

Dissipation, Residue Behavior and Dietary Risk Assessment of Difenoconazole on Jujube (Ziziphus jujuba Mill.)

Quantitative Analysis of Bioactive Compounds in Commercial Teas: Profiling Catechin Alkaloids, Phenolic Acids, and Flavonols Using Targeted Statistical Approaches

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