Residue dissipation and dietary risk assessment of trifloxystrobin, trifloxystrobin acid, and tebuconazole in wheat under field conditions

Feng, Yizhi; Qi, Xiaoxue; Wang, Xiao Yu; Liang, Lin; Zuo, Bojun

doi:10.1080/03067319.2020.1739667

Cited by 10 publications

(6 citation statements)

References 29 publications

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“…The national estimated daily intake (NEDI) of FPD and the RQ was calculated from the following equations:

NEDI ((),, mg / kg, bw) goodbreak= \frac{\sum ([], FI ((), kg) goodbreak\times STMR ((), mg / kg))}{bw ((), kg)}

RQ goodbreak= \frac{NEDI ((), mg / kg bw)}{ADI ((), mg / kg bw)}

where FI is the dietary intake for a certain type of food; STMR is supervised trials median residue; bw is the average body weight (63 kg); RQ is the risk quotient, and ADI is the acceptable daily intake (Feng et al, 2020; Liu et al, 2014; Ministry of Agriculture and Rural Affairs of the People's Republic of China, 2015).…”

Section: Methodsmentioning

confidence: 99%

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Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC–MS/MS

Feng

Zhang

Bian

et al. 2022

Biomedical Chromatography

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An effective method based on LC-MS/MS was established to determine the concentrations of flupyradifurone, difluoroacetic acid, and 6-chloronicotinic acid in pepper. On the basis of this method, the dissipation, processing factor, and dietary risk of flupyradifurone in pepper were investigated. The results show that the half-life of flupyradifurone in peppers was 2.6-3.8 days. The terminal residual concentration of flupyradifurone in the supervised trials was not higher than the maximum residue limit (MRL) for pepper in the Codex Alimentarius Commission (CAC) (0.9 mg kg À1 ) with the highest residual values of 0.53 mg kg À1 . The national estimated daily intake of flupyradifurone was 0.00094 mg kg À1 , based on the dietary structure of Chinese consumers and the terminal residues under field conditions. The risk quotient for flupyradifurone was 0.012, which was significantly < 1. The processing factor of flupyradifurone in dried pepper was 10.9-14.2, which indicated that drying increased the residual amounts of flupyradifurone in dried pepper, but the residual concentration was still lower than its MRL of 9 mg kg À1 established by CAC.

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“…The national estimated daily intake (NEDI) of FPD and the RQ was calculated from the following equations:

NEDI ((),, mg / kg, bw) goodbreak= \frac{\sum ([], FI ((), kg) goodbreak\times STMR ((), mg / kg))}{bw ((), kg)}

RQ goodbreak= \frac{NEDI ((), mg / kg bw)}{ADI ((), mg / kg bw)}

Section: Methodsmentioning

confidence: 99%

“…where FI is the dietary intake for a certain type of food; STMR is supervised trials median residue; bw is the average body weight (63 kg); RQ is the risk quotient, and ADI is the acceptable daily intake (Feng et al, 2020;Liu et al, 2014 The matrix effect (ME) of FPD, DFA, and 6-CNA was calculated according to the following formula:…”

Section: Calculation Formulamentioning

confidence: 99%

Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC–MS/MS

Feng

Zhang

Bian

et al. 2022

Biomedical Chromatography

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“…However, this method is only suitable for the pretreatment of fruits and vegetables with high water content [17]. Samples with low water content such as wheat grains and rapeseeds require the addition of a certain proportion of ultrapure water in the extraction process [18,22]. Also, since phthalanilic acid contains a carboxyl group, 0.1% formic acid is added to the extraction solvent to enhance extraction efficiency for better recovery [23].…”

Section: Optimization Of Extraction and Purification Conditionsmentioning

confidence: 99%

“…It has the advantages of rapidity, simplicity, and safety. e QuEChERS method has been widely used to analyze pesticide residues in food [18,19] and environmental samples [20]. Moreover, the QuEChERS method combined with LC-MS/MS has been used to determine the residues of phthalanilic acid in vegetables [13] and fruits [2]; however, there is no report on the application of the method for the analysis of pesticide residues in cereals and oilseed rape.…”

Section: Introductionsmentioning

confidence: 99%

Rapid Residue Analysis of Phthalanilic Acid in Cereals and Oilseed Rape by High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

Zhang

Zhou²,

Yu³

et al. 2022

Journal of Chemistry

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Phthalanilic acid is widely used in wheat and oilseed rape fields in China, but there is no analysis method to detect its residues in wheat and oilseed rape substrates. To accurately evaluate the health and environmental impact of phthalanilic acid residues on wheat gains and rapeseeds, it is urgent to establish a reliable analytical method for its detection. In this study, a rapid and sensitive method was developed based on QuEChERS and LC-MS/MS to detect phthalanilic acid in cereals (wheat, rice, corn, and millet), wheat straw, and rapeseeds. Optimization of the detection conditions showed that the mobile phase of acetonitrile-0.1% formic acid solution had the best chromatographic resolution and sensitivity. The average recovery rates of phthalanilic acid in cereals, wheat straw, and rapeseeds ranged from 88% to 113% with relative standard deviations (RSDs) of 1%–6%. There were good linear relationships with the correlation coefficients (r) higher than 0.9990 at concentrations of 0.01–5 mg L−1. The limits of quantification (LOQ) for phthalanilic acid in cereals, wheat straw, and rapeseeds were 0.01 mg kg−1, 0.05 mg kg−1, and 0.02 mg kg−1, respectively. These results show that the method established in this study is convenient and reliable for routine monitoring of phthalanilic acid in cereals, wheat straw, and rapeseeds.

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“…It has been reported that application of TFS on crops causes relatively high residues on potential feed materials. For example, the median residue level of TFS was 0.33 mg/kg in harvested rice hulls (Li et al, 2014) and was 0.31 mg/kg in wheat straw (Feng et al, 2020) at the recommended pre‐harvest interval of 28 days. TFS is fat soluble, which makes it accumulate more easily in animal meat and tissues through the food chain and environment.…”

Section: Introductionmentioning

confidence: 99%

Method validation, residue analysis and dietary risk assessment of trifloxystrobin and trifloxystrobin acid in milk, eggs and pork

Han

Qin

et al. 2022

Biomedical Chromatography

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Trifloxystrobin (TFS) is a widely used strobilurin fungicide and its residues accumulating in animal-derived food could result in potential harm to consumers. By optimization of extraction solvents and cleanup sorbents, a residue analysis method for TFS and its metabolite trifloxystrobin acid (TFSA) was established in milk, eggs and pork based on QuEChERS sample preparation and LC-MS/MS. The calibration curves exhibited good linearity with determination coefficients (R 2 ) >0.9930 over the range of 0.5-250 ng/ml for both TFS and TFSA. The recoveries of the two analytes were 81-100% with RSD 3-10% and 76-96% with RSD 2-13%, respectively. The limit of quantification (LOQ) was 1 ng/g for both analytes. The milk, egg and pork samples, 30 each, were collected from the 30 main producing regions in China, and residues of TFS and TFSA were analyzed. The concentrations of both analytes were lower than the corresponding LOQs and maximum residue limits. Long-term dietary risk assessment showed that the hazard quotients were 0.001-0.003%, indicating an absence of unacceptable risks in milk, eggs and pork to the health of common consumers in China.

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Residue dissipation and dietary risk assessment of trifloxystrobin, trifloxystrobin acid, and tebuconazole in wheat under field conditions

Cited by 10 publications

References 29 publications

Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC–MS/MS

Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC–MS/MS

Rapid Residue Analysis of Phthalanilic Acid in Cereals and Oilseed Rape by High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

Method validation, residue analysis and dietary risk assessment of trifloxystrobin and trifloxystrobin acid in milk, eggs and pork

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